Heart UK

This Week in Virology

This Week in Virology is a netcast about viruses - the kind that make you sick.

Vincent Racaniello

Roberto Cattaneo and Kalpana Yadav join TWiV at the 2026 meeting of the American Society for Virology to discuss how the absence of measles virus receptors in the brain selects for hyperfusogenic variants that spread neuron-to-neuron and cause subacute sclerosing panencephalitis, a rare but fatal long-term neurological sequela of measles infection. Host: Vincent Racaniello Guests:  Roberto Cattaneo and Kalpana Yadav Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV How measles virus adapts to the brain (Ann Rev Virol) Measles virus F50S change in neuronal spread (J Virol) Measles virus collective infectious unit and SSPE (J Virol) Measles virus brain tropism acquisition (PLoS Path) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1359: SSPE, the Long Shadow of Measles

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are angered by the continuous reporting of measles deaths in the US and around the world, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, establishing an NIH research center on vaccine harms, Legionnaires at Yankee stadium and the first time in more than half a century reporting of an equine screwworm case, and how HHS may prevent more than half of US children from getting the COVID-19 vaccine this season before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, efficacy and safety of the 2026-2027 COVID-19 vaccine, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts,  RSS, email  Become a patron of TWiV!    Links for this episode     Unvaccinated Woman  Likely Died of Measles Complications, Pa. County Coroner Says NY Times) Confirmed  death of an 18-year old due to complications of measles (Facebook: Mifflin County Coroner’s Office) CDC’s  new tracking method for measles deaths puzzles experts (CIDRAP) Kennedy to deliver keynote for  anti-vaccine group he once led (STATNews) Exclusive: New NIH research  center on vaccine harms takes shape (Science) US pediatricians report seeing fewer patients because of  immigration enforcement worries (CIDRAP) Surgeon General Nominee  Pledges Support for Vaccines in Senate Hearing (NY Times) CIDRAP Op-Ed: HHS is asking what to call  vaccine recommendations. You have 4 days to weigh in. (CIDRAP)  21,000 Unvaccinated Children Are Not a Minor Problem, But a Warning Sign (GPEI) Researchers file  First Amendment challenge to NIH grant screening (Science) Cooling towers at  Yankee Stadium test positive for Legionnaires’ in new cluster (NBC News)  Legionnaires’ Disease (NYC: Health) Dashboard  SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC  Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Texas ranch horse becomes nation’s  first confirmed equine New World screwworm case (Houston Chronicle)  Quick takes: Cautious optimism on Ebola, rare New World screwworm in a horse, HIV alert in Fiji (CIDRAP) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Notes from the Field: The  First 100 Days of Five Ebola Outbreaks — Democratic Republic of the Congo, Uganda, and West Africa, 2007–2026  (CDC: MMWR) Notes from the Field: Characteristics and Monitoring of the 2026 Outbreak of Ebola Disease Caused by Bundibugyo Virus —  Democratic Republic of the Congo, August 2026 (CDC:MMWR)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking  Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches  New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania)  Measles (Commonwealth of Pennsylvania) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Measles (CDC: Measles Rubeola) Adverse events associated with  childhood vaccines: evidence bearing on causality (NLM) Measles  Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the  evidence show (Vaccine) Measles in Bangladesh (microbeTV: TWIV)  Suspected measles cases kill nearly 1,000 as Bangladesh struggles to contain outbreak (AP News) Measles Cases and Outbreaks (CDC: Rubeola) Laboratory Testing for Measles (CDC: Measles (Rubeola) Measles Clinical Diagnosis  Fact Sheet (CDC: Measles (Rubeola) Measles  Serology Testing (CDC: Measles (Rubeola) Influenza: Waste water scan for  11 pathogens (WastewaterSCan) US  respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus  activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates  all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding  subclade K to fall shots (CIDRAP) Weekly surveillance report:  clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)  Early Antiviral Therapy in Pediatric Outpatients and Risk of Influenza-Related Hospitalization (Pediatrics) RSV: Waste water scan for  11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US  respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  RSV Immunization Effectiveness and Safety for the 2026-2027 Respiratory Season (JAMA) Waste water scan for  11 pathogens (WastewaterSCan) COVID-19  deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19  variant tracker (CDC) SARS-CoV-2  genomes galore (Nextstrain)  Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (Moderna) Novavax’s Partnership Strategy Continues to Deliver with  XFG-adapted Nuvaxovid™ Approvals in the U.S., EU and Japan for 2026-2027 Vaccination Season (novavax)  Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine (Pfizer) FDA  approves new COVID vaccines (CIDRAP) Covid Vaccines  Delayed for Half of U.S. Children (NY Times) COVID-19 Vaccine  Effectiveness and Safety for the 2026-2027 Respiratory Season (JAMA) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for  immunocompromised (ID Society) What to do when sick with a  respiratory virus (CDC) Managing healthcare staffing  shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s  evidence based medical practices for long COVID (OFID) Long COVID  hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to  US house representative Letters read on TWiV 1358 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!    Intro music is by Ronald Jenkees  Send your questions for Dr. Griffin to daniel@microbe.tv  Content in this podcast should not be construed as medical advice.

TWiV 1358: Clinical Update with Dr. Daniel Griffin

Paul Bieniasz joins TWiV to discuss his lab’s discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a frequency above 10⁻³ per genome, including new furin cleavage sites at the spike S1/S2 junction. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Genetic innovation in coronaviruses driven by a viral nuclease (bioRxiv) Letters read on TWiV 1357 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week  Kathy – Jurassic Museum of Asturias Alan – Grand Central Winter, by Lee Stringer Vincent – How to Choose REAL Extra Virgin Olive Oil: A Practical Guide and How to Tell if Your Olive Oil is Fake! Quick Kitchen Tip! Listener Pick  Shirley – I Told You So! by Matt Kaplan Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1357: Furin, Naturally with Paul Bieinasz

In his weekly clinical update, Daniel Griffin and Vincent Racaniello delve into dengue virus infections in Florida, recent human rabies infections in the US, proposed changes in biomedical funding including “converting” the Department of War into NIAID, the continuing controversy over the deaths of 2 children in Pennsylvania from measles, before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, approval of new mRNA COVID-19 vaccines by the FDA, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Dengue in Florida: Florida Arbovirus Surveillance (Florida Health) Nationwide Increase in Reported Human Rabies Exposures: Rabies Post-exposure Prophylaxis Administration (CDC: Health Alert Network) NIH proposes major revamp of how it scores research grant proposals (Nature) Revealed: inside the US military’s plan to tap huge sums from the NIH (Nature) Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey-Teen, United States, 2025 (CDC:MMWR) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Notes from the Field: Clinical Characteristics of Patients with Ebola Disease Caused by Bundibugyo Virus — Uganda, 2026 (CDC: MMWR) Notes from the Field: Characteristics and Monitoring of the 2026 Outbreak of Ebola Disease Caused by Bundibugyo Virus — Democratic Republic of the Congo, August 2026 (CDC:MMWR)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles vaccine recommendations from NYP (jpg)  Measles (Commonwealth of Pennsylvania) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Pennsylvania Department of Health Confirms Two Measles-Associated Deaths (Commonwealth of Pennsylvania) One of two measles-related deaths of unvaccinated people in Pennsylvania was an infant (CNN) Kennedy suggests measles deaths fabricated by PA governors (X) Measles Cases and Outbreaks (CDC: Rubeola) The CDC hasn’t added 2 deaths to its measles database Why? (Washington Post) Trump’s new CDC director ordered delay in counting 2 measles-related deaths (CNN) Commissioner Josh Parsons: Important information about measles (X) Laboratory Testing for Measles (CDC: Measles (Rubeola) Measles Clinical Diagnosis Fact Sheet (CDC: Measles (Rubeola) Measles Serology Testing (CDC: Measles (Rubeola) The Measles-Stricken Mother Who Lost Her Newborn Son (The Atlantic) What We Know About Pennsylvania’s Two ‘Measles-Associated’ Deaths (FactCheck.org) What Obstetric Health Care Providers Need to Know About Measles and Pregnancy (Obstetrics & Gynecology) Measles and Pregnancy: Immunity and Immunization—What Can Be Learned from Observing Complications during an Epidemic Year(Journal of Pregnancy) Measles in pregnancy (cmaj: Canadian Medical Association Journal) Physician’s Handbook on Medical Certification of Death (CDC: National Center for Health Statistics) CIDRAP Op-Ed: ‘Died with, not from’ was a real COVID problem. It’s the wrong framework for measles. (CIDRAP) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)  Early Antiviral Therapy in Pediatric Outpatients and Risk of Influenza-Related Hospitalization (Pediatrics) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (Moderna) Novavax’s Partnership Strategy Continues to Deliver with XFG-adapted Nuvaxovid™ Approvals in the U.S., EU and Japan for 2026-2027 Vaccination Season (novavax)  Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine (Pfizer) FDA approves new COVID vaccines (CIDRAP) COVID-19 vaccination and risk of post-COVID-19 cardiovascular disease: a population-based cohort and target trial emulation study (EHJ-QCCO) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1356 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1356: Clinical update with Dr. Daniel Griffin

TWiV reviews a landmark paper reporting the first generative design of complete viral genomes using AI, producing 16 viable bacteriophages that overcame antibiotic-resistant bacteria where natural phages could not, and a study suggesting that recombinant shingles vaccination reduces the risk of cardiovascular events. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Recombinant shingles vaccination reduces risk of cardiovascular events (Nat Med) AI design of bacteriophages (Science) AI-designed viral genomes (Science) Letters read on TWiV 1355 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week  Brianne – The Generative AI Learning Penalty: Evidence from Chinese Secondary Education Kathy – Ballista spider’s web to trap aggressive ants here and here Vincent – Microbecharmer from Sarah Listener Pick  Shirley – The Measles-Stricken Mother Who Lost Her Newborn Son Torsten – The battle over Covid’s origins has come for Bob Garry: A Top Virus Scientist Stared Down Covid Lab-Leak Proponents. Now His Life’s Work Is at Stake Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1355: Four billion years of AI training data

In his weekly clinical update, Daniel Griffin and Vincent Racaniello remember Dolly Parton and her patronage of science, especially development of the COVID-19 vaccines, if the shingles vaccine protect against cardiovascular events as well as dementia, the continued national cyclosporiasis and screwworm outbreaks, size of the Ebola outbreak in the Congo, the death of 2 children in Pennsylvania from measles and the economic cost of the measles outbreak, before Dr. Griffin deep dives into how to determine the case fatality rate of measles as well as measles outbreaks, recent statistics RSV, influenza, SARS-CoV-2 infections, approval of new mRNA COVID-19 vaccines by the FDA, access and how pay for Paxlovid, where to go for answers about long COVID-19, clinical guidelines for treating long COVID, B-cells-autoimmunity- long COVID, enrolling in a long COVID trial and the use of the COVID antiviral drug to “sop up” chronic virus shedding and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Dolly Parton adapts her song Jolene as she receives Covid-19 vaccine she helped fund (YouTube) Dolly Parton’s major contributions to vaccines and public health (the bmj) Recombinant shingles vaccination and the risk of cardiovascular events (Nature Medicine)  Surveillance of Cyclosporiasis (CDC: Cyclosporiasis) Infectious DiseaseOutbreaks (Michigan: Health & Human Services) Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Missouri Communicable Disease Report (2026) (Missouri Health) TWiP 285: Why is cyclospora hard to contain: Parasitologists explain the 2026 US outbreak (microbeTV:TWiP) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) FDA Issues Emergency Use Authorization for Generic Drug to Prevent New World Screwworm in Cattle(FDA) History of Ebola Outbreaks (CDC: Ebola) Democratic Republic of the Congo (OCHA) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania)  Measles (Commonwealth of Pennsylvania) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Two more kids die. And one more theater show. (Your Local Epidemiologist) RFK Jr. says Shapiro’s office may have fabricated measles deaths (Politico) ROBERT F. KENNEDY JR. SPEAKS OUT ABOUT VACCINES (Lancaster Patriot) Coroner says baby with measles in Pennsylvania died of a ruptured spleen (NBC News) Chapter 13: Measles (CDC: Epidemiology and Prevention of Vaccine-preventable Diseases) Challenges in measuring measles case fatality ratios in settings without vital registration (Emerging Themes in Epidemiology)  High attack rates and case fatality during a measles outbreak in groups with religious exemption to vaccination (The Pediatric Infectious Disease Journal) Oz: MMR vaccine ‘is not a lethal vaccine’ (The Hill) RFK Jr: Secretary of Measlesland (Substack: Beyond the Noise) ‘Brady Bunch’ episode fuels campaigns against vaccines and Marcia’s miffed (MPRNews) Use of Nowcasting to Estimate Real-Time Transmission Trends During a Measles Outbreak — South Carolina, October 2025–March 2026 (CDC:MMWR) Fighting measles is expensive. See what it cost to contain 10 cases (Washington Post) ‘An ounce of prevention is worth a pound of cure’ (Netherlands Heart Journal) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Heterogeneity of Airborne Virus Transmission in the Built Environment: A Narrative Review (Pathogens and Immunity)  Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (Moderna) Novavax’s Partnership Strategy Continues to Deliver with XFG-adapted Nuvaxovid™ Approvals in the U.S., EU and Japan for 2026-2027 Vaccination Season (novavax)  Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine (Pfizer) FDA approves new COVID vaccines (CIDRAP) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID A distinct effector B cell population drives autoantibody production in SARS-CoV-2 infection (Immunity)  Rapid recruitment for a remote long COVID clinical trial (LANCET:Infectious Diseases)  Insights from a double-blind, randomized, direct-to-participant intervention trial for Long COVID (medrxiv) Nirmatrelvir–ritonavir targeting viral persistence in post-COVID-19 condition (long COVID) in the USA (RECOVER-VITAL): a randomised, double-blind, placebo-controlled, phase 2 trial (LANCET: Infectious Diseases) Reaching out to US house representative Letters read on TWiV 1354 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1354: Clinical update with Dr. Daniel Griffin

TWiV explores how bacteriophages enable bet-hedge against bacterial immune defenses, and how transgenic mice engineered to produce human antibodies yielded potent anti-EBV candidates targeting gp350 and gp42, a promising step toward Epstein-Barr therapeutics. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Dolly Parton, and advocate for science (Nature) Phage bet-hedging (Nat Micro) EBV monoclonal antibodies (Cell Rep Med) Letters read on TWiV 1353 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week  Brianne – Did life on Earth emerge once or twice? Rich – Cassini Approaches Saturn (Wiki on Cassini) Jolene – Dolly Parton’s rewrite of Jolene song for vaccines on CBS news (Youtube) Vincent – Thinking, Fast and Slow by Daniel Kahneman Listener Pick  John – Dolly Parton Sings Vaccine, Vaccine Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1353: Phage bet-hedging and EBV antibodies

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are disheartened by the suggested change in federal vaccine recommendations, how Florida rolled back 4 childhood vaccine school requirements, results from a clinical trial suggesting that IPV can be used for outbreak control in IPV only countries, the continued national cyclosporiasis and screwworm outbreaks, size of the Ebola outbreak in the Congo, the death of 2 children in Pennsylvania from measles and the economic cost of the measles outbreak before Dr. Griffin deep dives into the use of monoclonal antibodies and remdesivir to treat Bundibugyo virus infection, measles outbreak, recent statistics RSV, influenza, SARS-CoV-2 infections, access and how pay for Paxlovid, , where to go for answers about long COVID-19, clinical guidelines for treating long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Request for Information: Categories Used in Federal Vaccine Recommendations and the Role of Shared Clinical Decision-Making (Federal Register) HHS Seeks Public Input on Federal Vaccine Recommendation Categories and Shared Clinical Decision-Making (US Department of Health and Human Services) HPV Vaccination and Risk of Head and Neck Cancers: A Large Real-World Cohort Study (International Society for Infectious Diseases)  Monkeypox Virus Surveillance — United States, 2024–2025 (CDC: MMWR) Clinical Trials (ClinicalTrials.gov) Effect of inactivated poliovirus vaccine on nasal mucosal immunity and pharyngeal shedding following novel oral poliovirus vaccine type 2 challenge: A randomized, open-label trial (JID) IPOL package insert (FDA) Florida Prepares to Roll Back School Vaccine Requirements (NOTUS) Florida’s Department of Health removes 4 vaccines from required list for public schools (CIDRAP)  Surveillance of Cyclosporiasis (CDC: Cyclosporiasis) Infectious Disease Outbreaks (Michigan: Health & Human Services) Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Missouri Communicable Disease Report (2026) (Missouri Health) TWiP 285: Why is cyclospora hard to contain: Parasitologists explain the 2026 US outbreak (microbeTV:TWiP) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola virus (AP News) What to know about the outbreak of a rare kind of Ebola (AP News) Congo’s Ebola outbreak is on track to surpass the deadliest one in history, WHO chief says (AP News) A look at major Ebola outbreaks and when the disease was first identified (AP News) Mobile gold miners in eastern Congo complicate health workers’ efforts to contain Ebola (AP News) How Congo is battling an Ebola outbreak complicated by aid cuts, armed rebels and anger (AP News) Here’s data showing Congo’s Ebola outbreak is on track to surpass history’s largest (AP News) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) A case of Bundibugyo virus disease treated with monoclonal antibodies and remdesivir (Nature Medicine) Post-Exposure Prophylaxis with a monoclonal antibody cocktail Following Bundibugyo Ebolavirus Exposure in Adults and Children (Nature Medicine)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania)  Measles (Commonwealth of Pennsylvania) Pennsylvania Department of Health Confirms Two Measles-Associated Deaths (Commonwealth of Pennsylvania) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Do vaccinated cases transmit measles? A systematic review and meta-analysis (Expert Review of Vaccines) County, district and community-level measles transmission in the United States in 2013−2025 (Nat Medicine) Quantifying the cost of measles outbreak in the U.S. and how costs scale with outbreak size (Vaccine) Each measles case in 2025 US outbreak cost almost $60,000, study estimates, or $134 million total (CIDRAP) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Cardiac outcomes following SARS-CoV-2 infection versus BNT162b2 vaccination in adolescents and young adults: a cohort study of 4 million individuals (Vaccine) mRNA COVID vaccine linked to lower risk of myocarditis in teens, youngadults (CIDRAP) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Trump Officials Falsely Connect Covid Vaccines to Miscarriage (NY Times)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1352 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1352: Clinical update with Dr. Daniel Griffin

TWiV describes a human cerebral organoid model for Ebola virus persistence, and brown bullhead catfish melanoma, a novel transmissible cancer. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Revamp of how NIH scores research grant proposals (Nature) Kansas BSL-4 lab faces more delays (Science) Ebola virus persistence in a human cerebral organoid model (Nat Micro) Hidden cost of immune privilege (Nat Micro) Transmissible melanoma of catfish (Nature) Skin cancer spreads between catfish (Nature) Tasmania devil cancer vaccine (Nature) Letters read on TWiV 1351 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week  Rich – The Faith of Beasts by James S.A. Corey Alan – Ingrained, by Callum Robinson Vincent – NYC’s 5 Broken Skyscrapers — Which One Dies First? Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1351: Ebola Virus Brains and Contagious Catfish Cancers

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are perplexed by the state of global public health as malaria, cholera and other infectious diseases are spread by civil warfare, the lack of manpower at the CDC to implement Congressional health programs, the first cancer mRNA vaccine resulting from a Merck and Moderna collaboration, how cyclosporiasis and screwworm outbreaks continue, FDA approval of new drugs against screwworm and critical policy decisions to control the Ebola outbreak in the Congo, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza, SARS-CoV-2 infections and the drop in vaccination rates in the US, how schools are the source of measles infection, how vaccines only prevent severe disease not transmission as trafficking of measles on vaccinated people begins to be acknowledged, to access and pay for Paxlovid, what to know about the mRNA flu vaccine, where to go for answers about long COVID-19, clinical guidelines for treating long COVID, three myths of respiratory disease and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Myanmar’s Civil War Pushes Infectious Disease Over Its Borders (NY Times) Alzheimer’s disease (AP News) US adult cigarette smoking rate hits another all-time low (AP News) The CDC has zombie programs. Congress funds them, but few people are left to do the work (AP News) Merck, Moderna’s personalized cancer vaccine slows recurrence in phase 3, setting up approval push (FIERCE Biotech)  Surveillance of Cyclosporiasis (CDC: Cyclosporiasis) Infectious DiseaseOutbreaks (Michigan: Health & Human Services) Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Missouri Communicable Disease Report (2026) (Missouri Health) TWiP 285: Why is cyclospora hard to contain: Parasitologists explain the 2026 US outbreak (microbeTV:TWiP) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newsroom) FDA Issues Emergency Use Authorization for Drug to Treat New World Screwworm in Dogs and Puppies (FDA) FDA grants emergency use authorization for another New World screwworm treatment (CIDRAP) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Three Months into the Bundibugyo Ebola Outbreak: Now is the time for Decisive Action (AfricaCDC)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Do vaccinated cases transmit measles? A systematic review and meta-analysis (Expert Review of Vaccines) County, district and community-level measles transmission in the United States in 2013−2025 (Nat Medicine) Dozens of States Tried to Roll Back Vaccine Laws. Here’s How They Fared. (NY Times) More U.S. Parents Opting Children Out of Vaccine Requirements, C.D.C. Reports (NY Times) The threat of more, expanded measles outbreaks looms with start of school (CIDRAP) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: clift notes (CDC FluView) What to Know About the mRNA Flu Vaccine, Newly Approved by the FDA (JAMA) Oseltamivir for Critically Ill Patients with Influenza: A Randomised Trial (LANCET)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis (LANCET) A national programme of bivalent prefusion F vaccination in pregnancy and protection against respiratory syncytial virus hospitalisation in infants until age 6 months in the UK: a multicentre, prospective, test-negative, case–control study (LANCET) Real-world studies show RSV immunizations protect newborns in their first year of life (CIDRAP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Trump Officials Falsely Connect Covid Vaccines to Miscarriage (NY Times)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Beyond the acute illness: three myths about viral respiratory infection (JID) Reaching out to US house representative Letters read on TWiV 1350 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1350: Clinical update with Dr. Daniel Griffin

TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in South America. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Fred Murphy, a pioneer in virology (J Virol) New midge-borne orthobunyavirus sickening cattle in Europe (Science)  What to Know About the Vaccines Targeted by Trump’s Executive Order (NY Times) What vaccine Executive Order gets wrong (CIDRAP) Trudy Rey’s 100th post at virology blog Transcriptional transition during phage SPO1 infection (Nucl Acids Res) Phase separation 101 (Iwasa lab) Early smallpox in America (Science) Letters read on TWiV 1349 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week  Brianne – APod August 7: Rubin’s Cosmos Field Rich – Jenner’s Inquiry  Original, “annotated”;  (PDF) Smallpox vaccination and opposition by anti-vaccination societies in 19th century Britain Jolene – Scott Seligmann’s web tool for searching keywords in podcast transcripts  Vincent – The End of Reading is Here Listener Picks  Tony – Fauci Fiasco Addendum Charles – The Proposed Changes in Childhood Vaccination: A Strongly Felt Opinion Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1349: Smallpox and mummies

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are troubled by the latest executive order changing routine childhood vaccine recommendations, the call for nominations to join the Advisory Committee for Immunization Practices, West Nile virus transmission in South Carolina, a newly identified midge-transmitted virus sickening cattle, and development of a cold-chain free DPT vaccine, the national cyclospora and screwworm outbreaks,new screwworm and genomics of Ebola outbreak in the Congo, and use of a mismatch vaccine to combat the Bundibugyo virus outbreak before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, where to go for answers about long COVID-19, clinical guidelines for treating long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  DELIVERING GOLD STANDARD CHILDHOOD VACCINE RECOMMENDATIONS FOR AMERICANS (Whitehouse) Trump signed an executive order calling for fewer childhood vaccines (NY Times) CIDRAP Op-Ed: What the vaccine executive order gets wrong, and what it will cost us (CIDRAP) New CDC director faces first major test before she even begins work (CIDRAP)  National Vaccine Advisory Committee (US Department of Health and Human Services) Solicitation of Nominations for Membership on the National Vaccine Advisory (Department of Health and Human Services) DPH Announces West Nile Virus Outbreak in Pee Dee South Carolina Department of Public Health)  Newly discovered virus is sickening cattle in Western Europe (Science) Safety, tolerability, and immunogenicity of SPVX02, a room temperature-stabilised tetanus-diphtheria vaccine, compared to two established tetanus-diphtheria booster vaccines: a multicentre, single-blind, randomised, first-in-human phase 1 trial in the UK (eClinicalMedicine)  Surveillance of Cyclosporiasis (CDC: Cyclosporiasis) Infectious DiseaseOutbreaks (Michigan: Health & Human Services) Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Missouri Communicable Disease Report (2026) (Missouri Health) TWiP 285: Why is cyclospora hard to contain: Parasitologists explain the 2026 US outbreak (microbeTV:TWiP) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Human Myiasis Resulting from Reemergence of Cochliomyia hominivorax Screwworm, Mexico, 2025–2026 (Emerging Infectious Diseases) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola)  Mismatched vaccine being rolled out against Ebola outbreak (Science) Emergence of a Bundibugyo virus variant in the 2026 outbreak in the Democratic Republic of the Congo and Uganda (Nature Medicine)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Kennedy Stirred Vaccine Fears in Pennsylvania Years Before Measles Outbreak (NY Times) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: clift notes (CDC FluView) Effectiveness of Oseltamivir in Hospitalized Children With Laboratory-Confirmed Influenza, 2014-2023 (JAMA Pediatrics)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID  Impact of COVID-19 Monoclonal Antibody Therapy on Subsequent Vaccine-Elicited SARS-CoV-2 Immune Responses (JID) Clinical practice guideline for long COVID prevention and treatment (ERS) Reaching out to US house representative Letters read on TWiV 1348 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1348: Clinical update with Dr. Daniel Griffin

TWiV explains research showing that Long COVID is associated with reactivation of numerous chronic viruses, including herpesviruses and anelloviruses, and with the production of autoantibodies that target neurological tissues. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Virus reactivation in acute and long COVID-19 (Cell) Association between autoantibodies and neurological symptoms in long COVID (Cell) Letters read on TWiV 1347 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week  Brianne – Merriam-Webster Time Traveler Feature Alan – The Incandescent, by Emily Tesh Vincent – How mosquitoes are conquering the world — in four charts Listener Picks  Vici – PBS Eons Charles – Entomologist Stephen Dobson on releasing modified mosquitoes to fight disease Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1347: No Short Answers for Long COVID

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz’ confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and resulting two deaths, new screwworm and the scale of the Ebola outbreak in the Congo, and clear results from some of President Trump’s policies dismantling public health activites including water safety, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, FDA approval of Moderna’s mRNA vaccine for seasonal flu, how to access and pay for Paxlovid, where to go for answers about long COVID-19, how SARS-CoV-2 infections may reactivate latent viral infections, particularly Aniello virus, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Senate confirms Erica Schwartz as CDC director (CIDRAP) PUBLIC HEALTH PREPAREDNESS: Experts Identified Actions to Improve Surveillance for Emerging Disease Threats (Government Accountability Office) Association Between First MMR Vaccination Before Age 2 Years and Childhood Autism in a U.S. EHR Cohort of 2.5 Million Children (The Pediatric Infectious Disease Journal) F.D.A. Approves Moderna’s mRNA Flu Vaccine (NY Times) Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults (NEJM)  Two Deaths Linked to Cyclosporiasis in Michigan (NY Times) CDC expands largest known cyclosporiasis outbreak to 15 states (Washington Post)  Surveillance of Cyclosporiasis (CDC: Cyclosporiasis) Infectious DiseaseOutbreaks (Michigan: Health & Human Services) Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Missouri Communicable Disease Report (2026) (Missouri Health)  Irrigation & Water Use (USDA: Economic Research Service) A Guide to OSHA’s Field Sanitation Standard (OSHA) Turm purge at FDA and USDA triggers food safety ‘brain drain’ (FOODNavigator)  Foodborne Illness Surveillance Systems (CDC) About Campylobacter infection (CDC: Campylobacter infection (Campylobacteriosis)) About Cyclosporiasis (CDC: Cyclosporiasis) About Listeria Infection (CDC: Listeria Infection (Listeriosis)) About Salmonella Infection (CDC: Salmonella Infection (Salmonellosis)) About Escherichia coli Infection (CDC: E.Coli Infection (Escherichia coli)) About Shigella Infection (CDC: Shigella-Shigellosis) About Vibrio Infection (CDC: Vibrio Infection (Vibriosis)) About Yersinia Infection (CDC: Yersinia Infection (Yersiniosis)) CDC Reveals Cause of Malaria’s Return to US After 20 Years(Newsweek) Trump Dismantles USAID: Experts Say Move Will Help America’s Rivals and Harm Millions (Newsweek) What we truly know about the huge US Cyclospora outbreak—and what we don’t (CIDRAP)  It’s The Water, Not Produce, Likely Driving Cyclospora Outbreaks (Forbes) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)  EBOLA: The Democratic Republic of the Congo, 2026(WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) EXCLUSIVE: Congo’s Ebola epidemic started at least 4 months before it was detected (Science)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Moderna’s mRNA flu shot mFlusiva snags FDA nod after refusal-to-file imbroglio (Fierece Pharma) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Household Transmission of SARS-CoV-2 in Washington and Oregon, United States, 2022-2024 (Journal of the Pediatric Infectious Diseases Society) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Virus reactivation in acute and long COVID-19 (Nature) Reaching out to US house representative Letters read on TWiV 1346 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1346: Clinical update with Dr. Daniel Griffin

TWiV travels to Colorado State University in Ft. Collins, where he speaks with Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein about their careers and their virology research. Host: Vincent Racaniello Guests: Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Susceptibility of wild and domestic songbirds to Usutu virus (PLoS NTD) Rabbit Hemorrhagic Disease Virus 2 Infection in Snowshoe Hares (J Wildl Dis) SARS-CoV-2 Delta variant transmission among red fox and striped skunk (Virology) Susceptibilities and viral shedding of peridomestic wildlife infected with clade 2.3.4.4b H5N1 (Virology) Socioeconomic benefits associated with bats (J Ethnobiol Ethnomed) Intrinsic factors driving mosquito vector competence (Front Cell Inf Micro) Modernizing the Toolkit for Arthropod Bloodmeal Identification (Insects) Can Bats Serve as Reservoirs for Arboviruses? (Viruses) The Case for Studying New Viruses of New Hosts (Ann Rev Virol) Rapid evolution of SARS-CoV-2 in domestic cats (Virus Evol) Safety study of Rift Valley Fever human vaccine candidate in mosquitoes (Transbound Emerg Dis) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1345: Rocky Mountain Virology High

In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the numerous attempts by states to roll back vaccine laws, the recent surge of Dengue virus cases in Sri Lanka, the national cyclospora outbreak, new screwworm and Legionnaires cases, launching of the CHaT-Ox Ebola vaccine trail, scale of the Ebola outbreak in the Congo and if cross-reactive Ebola antibodies are effective, before Dr. Griffin deep dives into the measles outbreak including the new Pennsylvania dashboard, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, where to go for answers about long COVID-19, how long COVID and ME/CFS differ and contacting your federal government representative to stop the assault on science and biomedical research.   Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Dozens of States Tried to Roll Back Vaccine Laws. Here’s How They Fared. (NY Times) Dengue cases in Sri Lanka surge past 80,000 (Newswire) After withdrawing false-positive test, FDA says Taylor Farms lettuce still a focus of Cyclospora investigation (CIDRAP) A difficult-to-trace parasite, messaging missteps contribute to summer of overwhelming Cyclospora outbreaks (CIDRAP)  Surveillanceof Cyclosporiasis (CDC: Cyclosporiasis) Infectious DiseaseOutbreaks (Michigan: Health & Human Services) Cyclosporiasis Cases in North Carolina (North Carolina: Division of Public Health) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Legionnaires’ Disease (NYC Health)  MAP UPDATE: 50 buildings in Manhattan outbreak zone test positive for live bacteria (NBC: News) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)  EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola)  First volunteer vaccinated in the world’s first Bundibugyo ebolavirus vaccine trial (University of Oxford)  Cross-Reactive Bundibugyo Antibody Responses after Receipt of Licensed Ebola Vaccines (NEJM)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Impact of Nirsevimab in Its Second Season on Respiratory Syncytial Virus and Non-RSV Admissions in Children Under 5 (Pediatric Infectious Disease Journal) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Remdesivir and All-Cause Graft Loss Among Kidney Transplant Recipients With Symptomatic COVID-19 (JAMA: Network Open)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest (Nature Communications) Loss of vesicular monoamine transporter 2 in striatum of long COVID and relationship to neuropsychiatric symptoms (eBioMedicine) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1344 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1344: Clinical update with Dr. Daniel Griffin

TWiV explains research which shows that Per os infectivity factors are essential for bracovirus infection and wasp parasitism, and that periodic shifts in viral load increase risk of Hendra virus spillover from Pteropus bats. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  Susumu Tonegawa Dies (Wikipedia)  Measles Cases Hit New Record in U.S., as Vaccination Rates Wane (NYTimes) Polydnaviruses on  on TWiVs 372 and 443 Per os infectivity factors essential for bracovirus infection and wasp parasitism (PNAS) Periodic shifts in viral load increase risk of Hendra virus spillover from Pteropus bats (Sci Adv) Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Kathy – A) Sign up for ScienceAdviser daily newsletter, free B) Goats DO get brain damage from head butting (Original bioRxiv preprint) Rich – This Star Just Ate a Planet, and It’s Not Done Yet Alan – Schisto and Ladders educational board game story, and the original publication on it. Vincent – How female dolphins know which males to avoid (Original article) Listener Pick David – What’s Under Your Feet in New York City? Ken – The usefulness of useless knowledge Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1343: Batting averages and stolen bases

In his weekly clinical update, Daniel Griffin and Vincent Racaniello explore the source/not source of the national cyclospora outbreak, trust in the FDA to correctly identify the source, new screwworm, Legionnaires and cyclosporasis cases, the Ebola outbreak in the Congo and development of a novel vaccine and antiviral before Dr. Griffin deep dives into the measles outbreak including the new Pennsylvania dashboard, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, difference between high and standard dose influenza vaccines, how to access and pay for Paxlovid, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  How helpful is not up to date? CDC: cyclosporiasis Taylor Farms pulls Mexican Lettuce on Cyclospora Cases (Bloomberg) FDA retracts positive cyclospora test on Taylor Farms lettuce (NPR: WHYY) False-positive lab sample DOES NOT change the basis for FDA’s ongoing outbreak investigation (X) FDA retracts test result but still links Taylor Farms lettuce to cyclosporiasis (Washington Post) Infectious Disease Outbreaks (Michigan: Health & Human Services) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Legionnaires’ Disease (NYC Health) Chapter 8: Cooling Towers (NYC Health) You can verify ifa person is licensed on the New York State Office of the Professions website: (NSPE-NY) Board for global EHS Credentialing (American Board of Industrial Hygiene) Water treatment vendor (Association of Water Technologies)  Cooling Towers: Information for Owners and Operators (NYC Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)  EBOLA:The Democratic Republic of the Congo, 2026(WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP’s Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Measles(CDC: Measles Rubeola) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Influenza vaccine effectiveness against outpatient acute respiratory illness withlaboratory-confirmed influenza, United States, 2024–25 season (CID) Effect of high-dose versus standard-dose influenza vaccines on hospitalisation outcomes and mortality in older adults: a systematic review and meta-analysis (LANCET: Healthy Longevity) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Randomized, Double-Blind, Placebo-Controlled First-in-Human Trial of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix (JID) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1342 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1342: Clinical update with Dr. Daniel Griffin

TWiV explains research that reveals dual activity of a phage-encoded lysin that modulates infection dynamics in a mycobacteriophage, and refutes a proposed link between the SARS-CoV-2 furin cleavage site and mouse-adapted MERS-coronavirus MA30. Hosts: Vincent Racaniello, Kathy Spindler, Angela Mingarelli, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Dual activity of phage-encoded lysin (mBio) Furin cleavage site and SARS-CoV-2 origins (PNAS) Theories on SARS-CoV-2 origins (CR Biol) Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Angela – Pigeons. An underappreciated animal. Superparamagnetic macrophages, cancer detectors, mirror mark test Kathy – Wednesday’s APOD and Graphene Jolene – Microbial Puppet Masters science exhibit, 3D-models linked in their paper Vincent – Beyond Inheritance by Roxanne Khamsi (TWiEVO 126) Listener Pick Lana – The Episodic Table of Elements Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1341: Phage breaks and COVID origins

In his weekly clinical update, Daniel Griffin and Vincent Racaniello debate if Senator Mitch McConnell’s recent hospitalization is due to post-polio syndrome or just old age, how air quality from Maine to Chicago has been affected by the Ontario wild fires, new screwworm, Legionnaires and cyclosporasis cases, the Ebola outbreak in the Congo and development of a novel vaccine and antiviral, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, where to go for answers about long COVID-19, long term effects of COVID-19 immune dysfunction including ocular and gut and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Statement From Senator Mitch McConnell (Mitch McConnell US Senator for Kentucky) Polio(NY Department of Health: Polio)  Global polio vaccination (CDC) For Some Survivors, Polio Casts a Long Shadow (GAVI) Former Republican Senate Majority Leader Mitch McConnell hospitalized (NPR) Hundreds of thousands of Americans live with the long-term effects of polio (CIDRAP) Child Care, Schools, Camps: Outdoor Air Quality Health Recommendations Based on Air Quality Index (NY City of Health: air quality)  Current Air Quality (AirNow)  Domestically Acquired Cyclosporiasis Cases in Multiple U.S. States, 2026 (CDC: Health Alert Network) How helpful is not up to date? CDC: cyclosporiasis Top 10 Cyclospora questions (Katelyn Jetelina: your local epidemiologist) Cyclospora, wildfire smoke, and another Legionella outbreak (Marisa Donnelly: your local epidemiologist in New York)  Cyclospora keeps climbing, a bad West Nile season, truck spraying, and good news (Katelyn Jetelina and Marisa Donnelly: your local epidemiologists) Infectious Disease Outbreaks (Michigan: Health & Human Services) Cyclospora cases up dramatically in New York (Outbreak News Today) Cyclospora Infection (Cyclosporiasis) (NYC Health)  Legionnaires’ Disease (NYC Health) New York officials find Legionella in 76 cooling towers as cases hit 63 (CIDRAP) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)  EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Why the fastest-growing Ebola outbreak in history is becoming more challenging (AP News) Oxford begins first human trial of Bundibugyo Ebola vaccine (Reuters) Gilead launches Ebola antiviral trial in DR Congo as cases near 2,000 (CIDRAP) Information for Travelers Returning from Ebola-Affected Areas (CDC: Ebola)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long-term ocular symptoms following COVID-19 linked to immune dysregulation, dysautonomia and peripheral neuropathy (Nature Communications) Vagal cholinergic denervationof the gastric mucosa in Long-COVID-19: in vivo evidence of structural autonomic dysfunction (International Journal of Infectious Diseases) Reaching out to US house representative Letters read on TWiV 1340 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1340: Clinical update with Dr. Daniel Griffin

Tom Ksiazek, a world-renowned virus expert with 40 years of experience on the front lines of some of the worst outbreaks the world has ever seen, joins TWiV to discuss his career, ebolaviruses in general, and the current outbreak of Bundibugyo ebolavirus in Africa. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Tom Ksiazek Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Fred Murphy passes (pdf) CJ Peters passes (pdf) Tom Ksiazek on TWiV 583 Letters read on TWiV 1339 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Brianne – APoD July 7: Dragons of Ara Rich – The Iconic Bass Riff That NOBODY Can Play; Riff (Wiki) see “Riff-Driven” Vincent – The song that made Carlos Santana a rock legend Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1339: Ebola up close with Tom Ksiazek

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are dismayed over the military deaths due to the voluntary influenza vaccination policy, FDA’s first vaccine recommendations since 2023, the efficacy of influenza vaccines, new screwworm, Legionnaires and cyclosporiasis cases, the Ebola outbreak in the DRC and Uganda and before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, publication of the blocked COVID-19 vaccine findings, where to go for answers about long COVID-19, use of antivirals in children with COVID-19, severe West Nile disease and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  A1C Keon Talik McDaniel (Bexar Memorial) Hegseth: Flu Vaccine Optional (US Department of War) Air Force trainee in San Antonio, Texas, died from flu(CIDRAP) Key FDA committee unanimously recommends its first vaccine since 2023(NPR) Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults (NEJM) Influenza Vaccine Effectiveness Against Pediatric Death in the United States: 2016–2025 (Pediatrics) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Upper East Side Legionnaires’ Outbreak Source Remains Unknown (Bloomberg) Outbreak of diarrhea-causing parasite grows to more than 1,000 cases (AP)  Cyclosporiasis outbreak in Michigan exceeds 1,000 cases (WOODTV+) Ebola deaths top 500 as DR Congo health workers threaten to strike (CIDRAP) Ebola deaths in Congo top 500 as health workers threaten to strike (AP) Ebola dashboard (ebola.fyi)   EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots(CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Nirmatrelvir/Ritonavir for the Treatment of COVID-19 in Children Aged 6 Years and Older (Pediatrics) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Efficacy and safety of rivaroxaban, colchicine, and famotidine–loratadine with specialist supportive clinical care for fatigue in patients with post-COVID-19 condition in the UK: a multisite, open-label, randomised controlled trial (LANCET: Infectious Diseases) Long-term Sequelae Associated With Severe West Nile Virus Disease in Maricopa County, Arizona, 2021 (OFID) Reaching out to US house representative Letters read on TWiV 1338 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1338: Clinical update with Dr. Daniel Griffin

TWiV explains research that reveals an an alternative evolutionary path of antiviral signalling in a sea anemone, and how a bacterial symbiont and a plant virus enhance insect fitness by inducing physical defenses against fungal parasites. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Springer-Nature retracted two papers by Max Planck, probably with a bot (Science) Alternative evolutionary path of antiviral signalling in sea anemone (Nat Ecol Evol) Bacterial symbiont and plant virus protect whitefly against fungal parasites (PNAS) Letters read on TWiV 1337 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Rich – The Mercy of Gods by James S. A. Corey; Livesuit by James S. A. Corey Alan – Climate.us, run by former NOAA scientists after Trump gutted their agency’s climate site Vincent – A Chemically Defined Synthetic Cell Capable of Growth and Replication Listener Pick Lana – The Episodic Table of Elements Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1337: The whitefly and the Red Queen

In his weekly clinical update, Daniel Griffin and Vincent Racaniello lament about the new ACIP charter, how administration of the HPV vaccine has eliminated cervical cancer deaths in young women, the global economic burden of infectious disease, restoring trust in vaccinology, new screwworm cases, the Ebola outbreak in the Congo and Uganda and need for preparedness, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, publication of the blocked COVID-19 vaccine findings, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  New ACIP charter broadens criteria for members, calls for review of alternatives to vaccines (STAT News) ACIP Charter (CDC: Advisory Committee on Immunization Practices) HPV vaccination eliminated cervical cancer deaths in young UK women in recent years, study suggests (CIDRAP) Cervical cancer mortality trends following HPV vaccination in England, 2001–24: an analysis of population-based mortality data (LANCET) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)  EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Size of the 2026 Ebola outbreak and risk of cross-border spillover from Bundibugyo virus in Ituri Province, DR Congo, and its implications for preparedness: a recalibrated stochastic modelling study (LANCET Infectious Diseases) US CDC raises Ebola outbreak response to highest level (Reuters) Construction of US-backed Ebola quarantine unit in Kenya is stopped (CIDRAP) ASPR Supports Global Ebola Response While Strengthening U.S. Preparedness (Administration for Strategic Preparedness & Response)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) US military requires flu vaccine for some after outbreak in Texas training center (Reuters)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1336 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1336: Clinical update with Dr. Daniel Griffin

Vincent speaks with Karen Torghele about her recently published biography of polio vaccine pioneer Albert Sabin, the first ever written. Host: Vincent Racaniello Guest: Karen Torghele Subscribe (free):  Apple Podcasts, RSS, email Links for this episode  Karen Torghele’s website Purchase Albert Sabin by Karen Torghele (Bookshop or Amazon) My letters from Albert Sabin (virology blog)  Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV Special: Albert Sabin with Karen Torghele

TWiV explains research showing how temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling, and that IgA antibody is necessary and sufficient to prevent norovirus infection in mice. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Fred Murphy passes away (X) US has lost its hold on measles elimination (CIDRAP) What’s in the genetic code of America’s measles outbreaks (ProPublica) Did Pete Hegseth single-handedly raise the R₀ of flu? (Inside Medicine) Fred Murphy’s Virus Images and Foundations of Virology (UTMB) Temperate phages and RNA-guided flagellar remodelling (Nat Micro) Eukaryotic RNA guided system (Nature) IgA prevents norovirus infection in mice (Sci Transl Med) Craig Wilen’s letter to TWiV (TWiV 492) Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Brianne – APod June 26: Milky Way Urban Style Rich – Your birth order affects your future, but not for the reason you think; Dr. McCoy Jolene – Bakteriopolis paper and site Vincent – The Claude Shutdown Is a Total Sh*tshow Listener Pick Martin – Ancient text charred by Vesuvius read for first time in 2,000 years Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1335: TldR, bacterial hot rods and nullifying norovirus

In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the global economic burden of infectious disease, restoring trust in vaccinology, the Legionnaires outbreak in Harlem, new screwworm cases, the Ebola outbreak in the Congo and Uganda and an import case into France, end of the hantavirus outbreak before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, outbreak of measles in Cook County Illionis in 2025, loss of measles elimination in the US, how to access and pay for Paxlovid, publication of the blocked COVID-19 vaccine findings, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Health and economic burdens of emerging infectious diseases in the USA, US territories and globally (BMJ Journal of Global Health) Meeting People Where They Are: Scientist-Creators Delivering Trusted Health Information on Social Media and Beyond (The Evidence Collective) Vaccine Integrity Project, The Evidence Collective announce projects to improve vaccine policy, restore trust (CIDRAP) Outbreak of Legionnaires’ Disease Associated with Cooling Tower Systems in Central Harlem (NEJM Evidence) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi)   EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) France confirms first Ebola case (BBC) Hantavirusdashboard (Hantavirus.up) Hantavirus on board with Prof. VincentRacaniello (microbeTV) Health agencies signal end of quarantine period for cruise-linked Andes virus outbreak (DG:Alerts) HHS Successfully Concludes Hantavirus Response Effort; Monitoring Ends with No Positive U.S. Case (US: HHS)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) US measles cases continue to climb, especially in Virginia (CIDRAP) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Measles (CDC: Measles Rubeola) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Measles Outbreak in Cook County, Illinois, September–October 2025 (NEJM Evidence)  CDC ‘transitioning away’ from diagnostic testing for measles, mumps (POLITICO PRO) CIDRAP Op-Ed: Call it what it is—the US has lost its hold on measles elimination (CIDRAP) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: clift notes (CDC FluView) US military requires flu vaccine for some after outbreak in Texas training center (Reuters)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) CDC’s chief blocked a covid vaccine study. Now it’s in a top medical journal. (Washington Post) Interim Estimated Effectiveness of 2025-2026 COVID-19 Vaccines in Adults Using a Test-Negative Design (JAMA Network: OPEN) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1334 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1334: Clinical update with Dr. Daniel Griffin

TWiV explains research showing how HIV-1 signalling remodels nuclear pores to licence infection, and development of STING agonist nanoparticles to enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection. Hosts: VVincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  Bundibugyo ebolavirus sitrep (WHO) Ebolavirus and Andes virus with John Dye (TWiV Special) Major research nonhuman primate supplier going out of business (Science) HIV-1 signalling remodels nuclear pores to licence infection (Nature) STING agonist nanoparticles enable mucosal-systemic immunity (Nature Nanoparticles) Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Brianne – Otherworldly music albums feature space weather data Rich – Evidence Mapping: Consolidating and summarising available evidence to support the demonstration of effectiveness of developmental vaccines, Australian Living Evidence Collaboration (ALEC) Alan – Holyoke dam fish elevator Vincent – 68 Quadrillion Underground Miles of Fungi Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1333: STING like a nanoparticle, float like HIV

Vincent travels to ASM Microbe in Washington DC to speak with John Dye of the United States Army Medical Research Institute of Infectious Diseases about the recent outbreaks of Bundibugyo ebolavirus in Africa and Andes virus on a cruise ship. Host: Vincent Racaniello Guest: John Dye Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV Special: Ebola virus and Andes virus with John Dye

In his weekly clinical update, Daniel Griffin and Vincent Racaniello express concern  about vaccine policy and ACIP, scaling back of the CDC’s role in global public health, shingles vaccine and dementia, new screwworm cases, the Ebola outbreak in the Congo and Uganda and where the hantavirus outbreak began, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Virgina outbreak of measles, how to access and pay for Paxlovid, how more people were negatively impacted by influenza than COVID, discontinuing contact precautions for COVID, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Today we filed a motion asking the First Circuit to expedite our appeal of the district court’s order in the AAP lawsuit that left ACIP—the nation’s vaccine advisory committee—without a quorum (X)  CDC advisers drop decades-old universal hepatitis B birth dose recommendation, suggest blood testing after 1 dose (CIDRAP) HHS asks for expedited appeal of court ruling on US vaccine policy (CIDRAP) New Plan Scales Back C.D.C.’s Work on Diseases Abroad (NY Times) Zoster Vaccination and Dementia: Interpreting the Signal and Testing the Mechanisms (CID) Safety and Immunogenicity of 1 or 2 Additional Doses of the Adjuvanted Recombinant Zoster Vaccine Administered 5–6 Years After Primary Vaccination in Adults ≥50 Years (OFID) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Head-to-head comparison suggests flu was much more likely to lead to hospitalization than COVID last winter (CIDRAP) FDA Issues Emergency Use Authorization for Generic Over-the-Counter Drug to Treat New World Screwworm in Dogs and Cats (FDA) Fact Sheet: Emergency Use Authorization of Nitenpyram Tablets (nitenpyram) for New World Screwworm (NWS) (FDA) Ebola dashboard (ebola.fyi)   EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola)  Big Ebola outbreak puts spotlight on little known virus (Science) Ebola outbreak spreads to crowded displacement camp in Congo (Reuters) Ebola outbreak in DR Congo expands into large displacement camp (CIDRAP) Congo Ebola outbreak may be worst ever, Africa CDC says (Reuters) Advocacy groups are urging the release of the monoclonal antibody MBP134 and any other requested investigational therapeutics (Citizen.org) Hantavirus dashboard (Hantavirus.up Hantavirus on board with Prof. Vincent Racaniello (microbeTV) How did the cruise ship hantavirus outbreak start? (Science)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard( South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) US measles cases continue to climb, especially in Virginia(CIDRAP) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Anguished Parents, Crying Doctors: Life Amid Utah’s Measles Outbreak (Wired) Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, January–March 2025 (CDC:MMWR) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: clift notes (CDC FluView) Influenza Vaccine and Associated Infection and Death in California, 2024 to 2025 (JAMA Network OPEN)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Seasonal influenza versus COVID-19 hospitalisation risk during the 2025–26 influenza season (LANCET: Infectious Diseases)  Discontinuingcontact precautions for COVID-19: the science says its time (Infection Control and Hospital Epidemiology) 2024-2025 COVID-19 Vaccine and Major Adverse Cardiovascular Events Among US Veterans (JAMA Internal Medicine) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1332 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1332: Clinical update with Dr. Daniel Griffin

TWiV explains research showing that dairy cows are infected with low doses of influenza A(H5N1) and do not transmit efficiently to other animals, and covalent inhibitors of human papillomavirus type 16 E6 protein that restore p53 function and suppress growth of HPV-driven tumors in vivo. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  Letter on Baric funding ban (Science, scroll to bottom)  New political jobs at science agencies (Science)  Ebola sitrep (WHO) Influenza H5N1 infection of dairy cows (Nat Comm) Drug for cervical cancer (PNAS) Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Angela – SpaceX Brianne – Honeybees and shrimp are now getting vaccinated Rich – “Carrying the Fire: An Astronaut’s Journeys” by Michael Collins Vincent – NTSB Reveals What Really Happened to United 169 Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1331: A drug for cervical cancer

In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined “Hantavirus” patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Childhood Vaccine Hesitancy (NEJM) One Year In: Public Views of a Changing Public Health Landscape (Harvard School of Public Health)  Rotavirus Vaccine Coverage and Potential Barriers Among US Children Born From 2007 to 2024 (Pediatrics) Texas reports New World screwworm in 3-week-old calf (CIDRAP) USDA Confirms First Case of New World Screwworm in a Dog in Lea County, New Mexico, Fourth Case in Texas (USDA: Animal and Plant Health Inspection Service)  Confirmed Detections of New World Screwworm (USDA: Animal and Plant Health Inspection Service) Mexico reports more human New World screwworm infections (CIDRAP) Frequency and persistence of post-acute symptoms after chikungunya, dengue, Zika and malaria in travellers: a prospective multi-centre study (Journal of Travel Medicine) Ebola dashboard (ebola.fyi)   EBOLA:The Democratic Republic of the Congo, 2026 (WHO)  Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Modeled Scenario Projections for the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026 (CDC: MMWR) Assessment of Riskto the U.S. Population from the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026 (CDC: MMWR) How Ebola Disease Spreads (CDC: Ebola) Signs and Symptoms of Ebola Disease (CDC: Ebola) Hantavirusdashboard (Hantavirus.up) Hantavirus on board with Prof. VincentRacaniello (MicrobeTV) Some hantavirus-exposed cruise ship passengers return home to finish quarantine (CNN) Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons (LANCET: Infectious Diseases) First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Anguished Parents, Crying Doctors: Life Amid Utah’s Measles Outbreak (Wired) Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, January–March 2025 (CDC:MMWR) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Real-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France (LANCET: Microbe) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national andregional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Shionogi Announces FDA Approval of XOCOVA® (ensitrelvir), the First and Only Oral Option to Help Prevent COVID-19 Following Exposure (Businesswire) SARS-CoV-2 viral shedding and vaccination‑modified effects of oral antivirals in older COVID-19 patients: a retrospective cohort study in Hong Kong (International Journal of Infectious Diseases) SARS-CoV-2 vaccination and attenuation of breakthrough infection severity: A systematic global review and meta-analysis (CID) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID  Metformin on the Presence of COVID-19 Symptoms 6 Months after Infection: The ACTIV-6 Randomized Clinical Trial (CID) Reaching out to US house representative Letters read on TWiV 1330 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1330: Clinical update with Dr. Daniel Griffin

TWiV explains research showing limited transmission of cervid prions to nonhuman primates, and the finding that cone-shaped HIV-1 capsids are transported through intact nuclear pores. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Ebola outbreak news (ECDC, WHO) NSF research grants on hold (Nature) Transmission of cervid prions to nonhuman primates (Sci Adv) Cone-shaped HIV-1 capsids transported intact through nuclear pore (Cell) HIV-1 reproduction video (Janet Iwasa) Letters read on TWiV 1329 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Brianne – What We Need to do NEXT Re: OMB Rule Alan – Metallic Realms, by Lincoln Michel Vincent – TWiV 1: West Nile Virus Listener Picks Mark – How the Library of Congress packed 250 years of U.S. history into a vial the size of a quarter Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1329: How HIV-1 goes nuclear

In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined “Hantavirus” patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  CIDRAP Op-Ed: What’s the likely next move after the executive order on childhood vaccines? (CIDRAP) Ebola dashboard (ebola.fyi) Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO) WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Race begins to trial Ebola drugs amid current outbreak (Nature)  Three Ebola vaccine candidates fast-tracked as African outbreak continues (CIDRAP) CEPI fast-tracks three Bundibugyo ebolavirus vaccine candidates (CEPI) Obeldesivir (Wikipedia) Hantavirusdashboard (Hantavirus.up) Hantavirus on board with Prof. VincentRacaniello (microbeTV) Scoop: HHS asks confined hantavirus cruise passengers to assist in propaganda (Inside Medicine) Ribavirin (DrugBank) First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (IDSA) Deaths following vaccination: what does the evidence show (Vaccine) Bangladesh posts more than 1,300 measles cases, 2 deaths, in 1 day (CIDRAP) Measles Outbreak in a Child Care Facility — Lubbock, Texas, March–April 2025 (CDC:MMWR) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Shionogi Announces FDA Approval of XOCOVA® (ensitrelvir), the First and Only Oral Option to Help Prevent COVID-19 FollowingExposure (Businesswire) FDA Approves Oral Antiviral to Prevent COVID-19 After Exposure (MEDPAGE TODAY) The impact of COVID-19 vaccination on long-term risk of new-onset atrial fibrillation/flutter after COVID-19 infection: A retrospective cohort study (PLoS One) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) TWiV 739: COVID-19 convalescent plasma with Arturo Casadevall (microbeTV) COVID-19 L*OVE: the largest open repository of evidence on this pandemic (Epistemonikos) Convalescent plasma for people with COVID‐19 (Cochrane Library) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1328 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1328: Clinical update with Dr. Daniel Griffin

TWiV explains research on human influenza virus transmission that reveals heterogeneous expulsion of infectious virus into air, and how gut bacteriophages dictate inflammation heterogeneity through tuning the phage-bacteria-sphingosine-intestine axis in Crohn’s disease. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) NIH ousts infectious-disease leaders (Nature)  Measles deaths in Bangladesh (npr) Russel Vought is going to destroy American science (Elizabeth Ginexi) Heterogeneous expulsion of infectious influenza virus into air (Cell)  Gut phages and Crohn’s disease (Cell Host Microbe) MIST device (Emory) Letters read on TWiV 1327 Timestamps by Jolene Ramsey. Thanks!  Picks of the Week Brianne – The Perfect Bee Language Rich – Hubble’s Messier Catalog Jolene – A different kind of power – Jacinda Ardern Vincent – Albert Sabin by Karen Torghele Listener Picks Anthony – Dr. Dakotah Tyler Marcus – Apollo Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1327: Influenza viruses in the MIST

In his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda including vaccine candidates before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Texas in 2025, how to access and pay for Paxlovid, where to go for answers about long COVID-19, casual association of auto-antibodies and COVID complications and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria — United States, 2026 (CDC: MMWR) Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases) Hantavirusdashboard (Hantavirus.up) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases) Hantavirus on board with Prof. VincentRacaniello (microbeTV) Ebola dashboard (ebola.fyi) Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO) WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo) WHO chief says fast-moving Ebola epidemic is outpacing response efforts (Reuters) US CDC seeks staff for Ebola screening as outbreak response expands (Reuters) Trump Administration to Send Americans Exposed to Ebola to Kenya (NY Times) Single Immunization With a Monovalent Vesicular Stomatitis Virus–Based Vaccine Protects Nonhuman Primates Against Heterologous Challenge With Bundibugyo ebolavirus (JID) Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus (PLoS Neglected Tropical Diseases) Vaccine experts debate options to combat outbreak of unusual Ebola strain (Science) NIAID Establishes Centers for Research in Emerging Infectious Diseases (NIAID.NIH) Inside the Race to Develop a Test for the Rare Andes Hantavirus (Wired) NIH terminates network aimed at stopping pandemics before they start (Science) These Researchers Would Be in Africa Fighting Ebola—but Trump Cut Their Funding (Wired)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, January–March 2025 (CDC:MMWR) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) US FDA advisers to weigh updating 2026-27 COVID vaccines for XFG variant (Reuters) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID A causallink between autoantibodies and neurological symptoms in long COVID (Cell) Reaching out to US house representative Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1326: Clinical update with Dr. Daniel Griffin

Vincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences transmission. Hosts: Vincent Racaniello Guest: Hannah Rowe Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Respiratory bacteria stabilize influenza A virus (mSystems) S. pneumoniae and influenza A virus binding (mSphere) Bacterial alteration of redox stressors and stability of influenza A virus (mSphere) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1325: Sticky flu with Hannah Rowe

In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss withdrawal of the ACIP charter published in April 2026, the first council meeting on antibiotic resistant bacteria, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, transmission of SARS-CoV-2 through the air including ventilation systems, how to access and pay for Paxlovid, where to go for answers about long COVID-19, early use of antiviral drugs for COVID-19 patients and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  US health department withdraws vaccine advisory panel charter (Reuters) Meeting of the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (Federal Register) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases) Hantavirus on board with Prof. VincentRacaniello (microbeTV) Hantavirus Doesn’t Spread Easily, but Officials May Be Downplaying Risks (NY Times) Cross-binding antibodies capable of neutralising diverse hantaviruses are produced in response to Puumala virus infection (eBioMedicine) Hantavirus dashboard (Hantavirus.live) Visualizing the hantavirus cruise outbreak in maps and charts (CNN) Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO) Ebola outbreak response intensifies in DRC and Uganda as cases mount (DG: Alerts) WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo) Vaccine experts debate options to combat outbreak of unusual Ebola strain (Science) US promises to fund clinic established to treat Ebola (X-USForeignAssist) U.S.-Bound Flight Diverted to Canada Because of Ebola Restrictions (NY Times)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health)  Maternal RSV Vaccination, Infant Nirsevimab, or Both: Interim Analysis of a Randomized Trial (Pediatrics) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Potential airborne transmission of SARS-COV-2 through bathroom ventilation ducts associated with an outbreak in a residential building in Santander, Spain, 2020 (PLoS One) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  Recent COVID-19 Vaccination and Risk of SARS-CoV-2 Transmission (JAMA Network OPEN)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Early antiviral use may lower risk of long COVID in mildly ill patients, aid recovery from infection (CIDRAP)  Early-Phase Oral Antiviral Use and Post–COVID-19 Condition in Outpatients (JAMA Network OPEN) Impact of Early Oral Antiviral Use for Outpatients With COVID-19 on Healthcare Utilization and Recovery (ANCHOR-02) (International Journal of Infectious Diseases) Reaching out to US house representative Letters read on TWiV 1324 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1324: Clinical update with Dr. Daniel Griffin

TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity, Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) RFK Jr. driving vast inquiry into vaccines (NY Times) Indiana plant biologist locked out of lab by school (Science) Trump cuts CDC role in PEPFAR (Science)  Ralph Baric retires (The Assembly) Baric to fight NIH funding ban (Science)  Ebola outbreak in DRC (npr) Persistence of Andes virus RNA in human semen (Viruses) mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines (Cell Rep) Science will break your heart (TWiV 920) TLR7 and maternal and fetal morbidity during influenza (Sci Adv) Letters read  on TWiV 1323 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Kathy – Bloomberg Connects app and What’s in Bloom  Peony Season 2026 Bloom Tracker Rich – Medpage Today: What you need to know about hantavirus Vincent – Apollo 11 Almost Never Left the Moon Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1323: One influenza infection, two patients

In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and Prevention for the management of infectious cases, whether the CDC may be downplaying the significance of the outbreak because of public backlash following the COVID-19 pandemic, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, benefit of maternal vaccination against RSV for infants, efficacy and safety of a mRNA influenza vaccine  how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Interim Guidance for Public Health Assessment and Management of People with Potential Exposure to Andes Virus Outbreak (CDC) Hantavirus in humans: a review of clinical aspects and management (LANCET: Infectious Diseases) “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases) Hantavirus on board with Prof. Vincent Racaniello (microbeTV) Transcript – Updateon CDC’s Hantavirus Response 5/13/2026 (CDC) CDC Is Walking a Tightrope With Its Response to Hantavirus (Wall Street Journal) What Happened on the Hantavirus Cruise, According to a Doctor On Board (The Atlantic)  Andes hantavirus outbreak on a cruise ship – an ESCMID Emerging Infections Subcommittee (EIS) rapid assessment (CMI: Clinical Microbiology and Infection)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults (NEJM)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health)  Maternal RSV Vaccination, Infant Nirsevimab, or Both: Interim Analysis of a Randomized Trial (Pediatrics) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Life lost due to the COVID-19 pandemic: A model-based cohort analysis of mortality displacement in the registered population of England (PLoS One) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts (NEJM)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1322 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1322: Clinical update with Dr. Daniel Griffin - Hantavirus special

TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Craig Venter dies (Nature)  Hantavirus outbreak (WHO) Hantavirus on board (YouTube) HPS 25th anniversary discovery story (EID) Phage therapeutic failure unraveled (Nat Med) Phages communicate across species (Cell) Control of lysis-lysogeny decisions (Trends Micro) Arbitrium phages manipulate each other (Cell) Elio Schaechter on arbitrium (TWiM 146) Letters read  on TWiV 1321 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Could this fungus contaminate Mars? Rich – Supernova in a Sideways Spiral Jolene – Virology class communication projects 2026 Vincent – Facts About The Boeing 747 Hump That Will Surprise You Listener Picks David – My first science video in 3 years  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1321: Phage cross talk and cross reactions

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the outbreak of Hantavirus on a cruise ship and its potential for person-person transmission, how cessation of funding for global health by the Trump administration has compromised American health and well being, as well as the description of paralytic poliomyelitis outbreaks in Central Africa associated with the administration of nOPV2, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, association of ear infections in children with RSV, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Hantavirus Pulmonary Syndrome—The 25th Anniversary of the Four Corners Outbreak (CDC: Emerging Infectious Diseases) Outbreak of Hantavirus Infection in the Four Corners Region of the United States in the Wake of the 1997–1998 El Nino—Southern Oscillation (JID) Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases) Hantavirus cluster linked to cruise ship travel, Multi-country (WHO)  Hantavirus (WHO)  Ventilation Upgrade Reduces Fuel Consumption by 10 Percent in Cruise Ships(Halton) Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases) Incubation Period of Hantavirus Cardiopulmonary Syndrome (CDC: Emerging Infectious Diseases) At least 8 sickened in suspected hantavirus outbreak; Andes strain confirmed (CIDRAP) Hantavirus in humans: a review of clinical aspects and management (LANCET: Infectious Diseases) Cruise ship’s hantavirus outbreak puts researchers in uncharted territory (Science) Hantavirus Response Shows How Trump Cuts Have Compromised U.S. Preparedness (NY Times) Hantavirus on board with Prof. Vincent Racaniello (microbeTV) Emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic (mBio) TWiV 1319: An earful of SARS-CoV-2 (microbeTV)  Poliomyelitis (polio) (WHO) The world’s largest and ​highest-quality​​ first-party data company (Dynata) MMR vaccine hesitancy in a polarized information ecosystem: Results from a cross-sectional survey of US adults (Vaccine) CDC communication undermines trust in vaccines (Science)  F.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were Safe (NY Times)  Tick Bite Data Tracker (CDC: Ticks)  Infectious Diseases (POPHIVE: Yale School of Public Health) The National Respiratory and Enteric VirusSurveillance System (NREVSS) (CDC: National Respiratory and enteric virus surveillance System)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Will the USA lose its measles elimination status? (LANCET) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Impact of Respiratory Syncytial Virus Immunization on the Rate of Pediatric Acute Otitis Media: A Time-series Analysis (CID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID  Multisystem inflammatory syndrome in children (MIS-C), United States, 2023–2024 (CID) Current status and future perspectives on the mechanistic and pathophysiological understanding of long COVID (Communications Medicine) Reaching out to US house representative Letters read on TWiV 1320 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1320: Clinical update with Dr. Daniel Griffin

TWiV explains the emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic, and the infection of spiral ganglion neurons in the inner ear by SARS-CoV-2, which may explain hearing loss in humans. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  Bernard Roizman dies (U Chicago)  Craig Venter dies (Sci Am) Trump fires National Science Board (AAU) It was World Vaccine Week (WHO) nOPV2 phenotypically reverts via recombination (mBio) SARS-CoV-2 infects inner ear (Cell Rep) Letters read  on TWiV 1319 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Kathy – Science of rats and other organisms in the East River Alan – Chronolog citizen science project Vincent – Why Do Train Engines Sometimes Face Backwards? Listener Picks Chris – Consensus: AI for research  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1319: An earful of SARS-CoV-2

In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global research powerhouse; ongoing advances and controversies in vaccines shaped by the World Health Organization and the Centers for Disease Control and Prevention; vaccine policy battles in Florida; European approval of the moderna mCOMBRIAX, COVID-19 and influenza vaccine, the mounting evidence supporting preventive vaccination strategies including that for HPV and the HepB birth dose; the spread of drug-resistant infections and the resurgence of HIV in Zambia; and the enduring public trust in scientists despite political turbulence, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the efficacy of the influenza vaccine for children, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, use of remdesivir for RSV, how administration of Paxlovid did not affect hospitalization of high-risk vaccinated patients, where to go for answers about long COVID-19, if SARS-CoV-2 infection may facilitate EBV reactivation, exercise for treating long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Entire NSF science advisory board fired by Trump administration (Nature)  United States v. Arthrex, Inc.(Harvard Law Review) United States v. Arthrex Inc. [SCOTUSbrief] (Federalist Society) China could be the world’s biggest public funder of science within two years (Nature) The Vaccine Skeptic in Trump’s New C.D.C. Leadership Team (NY Times) World Immunization week: Largest catch-up initiative delivers over 100 million childhood vaccinations (WHO) Pigs are flying!: Florida Republicans refuse to take up DeSantis bill loosening vaccine mandates (NY Times) Moderna Receives European Commission Marketing Authorization for mCOMBRIAX, Moderna’s mRNA Combination Vaccine Against Influenza and COVID-19(moderna) America First! AIDS Creeps Back in Parts of Zambia, a Year After U.S. Cuts to H.I.V. Assistance (NY Times) Emergence of Extensively Drug-Resistant Shigellosis — United States, 2011–2023 (CDC: MMWR) Scientists Esteemed by Public, with Vaccine Scientists Seen as Similar to Scientists in General (Annenberg: Public Policy Center, University of Pennsylvania) RFK Jr. is holding up $600M in vaccines for poor countries (Politico) Trump Withdraws Nomination of Casey Means for Surgeon General (NY Times) What? Benefit of preventive strategies like vaccination? Incidence of human papillomavirus infections in women aged 27 years and older in the US: A federated data network study (International Journal of Infectious Diseases) Economic Impact of Delaying the Infant Hepatitis B Vaccination Schedule (JAMA Pediatrics)  Impact of Removing the Universal Hepatitis B Birth-Dose Vaccination in the US (JAMA Pediatrics)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola)  Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine)  Dangers of measles infection (NY Times) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza)  Influenza Vaccination Coverage Among Nursing Home Residents and Health Care Personnel — United States, 2024–25 Influenza Season (CDC: MMWR)  Pediatric Vaccine Effectiveness Against Influenza Hospitalization And Outpatient Visits: 2021–2024 (Pediatrics) Influenza Vaccine Effectiveness in European Primary Care Pediatric Practices: 2022–2024 (Pediatrics) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (LANCET: Infectious Diseases) First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients(NEJM) Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir(NEJM) Paxlovid doesn’t reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia: Columbia University Irving Medical Center) The answers: Long COVID Acute COVID-19 is associated with altered CD8 T-cells indicative of impaired ability to control Epstein–Barr virus reactivation (Medical Microbiology and Immunology) Exercise and Weekly Sirolimus (Rapamycin) in Older Adults: RAPA-EX-01 Randomised, Double-Blind, Placebo-Controlled Trial (Journal of Cachexia, Sarcopenia and Muscle) Reaching out to US house representative Letters read on TWiV 1318 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1318: Clinical update with Dr. Daniel Griffin

TWiV explains a study showing that viral DNA load in blood and saliva varied markedly with age, time of day season, sex, and depended on dozens of genetic loci, and identification of an emerging human eye disease associated with aquatic virus zoonotic infection. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) DNA virome varies with human genes and environments (Nature) Emerging eye infection from aquatic virus (Nat Micro) Letters read  on TWiV 1317 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Wayback Machine: Internet Archive Rich – Grandparents for Vaccines Alan – On Writing by Stephen King Vincent – The Real Reason The Soviets Lost The Space Race! Listener Picks Ginny – Dr. Cal Your Science Pal  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1317: Dead shrimp walking

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are distressed by RFK Jr’s testimony in front of Congress, surges in rotavirus infections and the staggering number of people who believe in unproven claims about vaccines and science, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the fatal consequences of measles infection, prevalence of influenza and other respiratory infections in dead people, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, results from a human RSV challenge study, where to go for answers about long COVID-19, negatively associated school-related outcomes in children and adolescents with long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Kennedy denies being sidelined by the White House (Politico) Kennedy continued to back away from his criticismof the measles vaccine (NY Times) Rotavirus surges after ACIP removes recommendation for vaccine(Discovermagazine) ‘Staggering’ number of people believe unproven claims about vaccines, raw milk and more (Nature) Health is confronting division, confusion, and competing influences (Edelman)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine)  Dangersof measles infection (NY Times) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)  Prevalenceof influenza and other respiratory viral infections in deceased persons: a population-based observational study over four influenza seasons (Clinical Microbiology and Infection) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Maternal RSV vaccination and reduced risk of hospitalisation for babies in England, 2024/25 (ESCMID)  Viral dynamics of the Respiratory Syncytial Virus during experimental human challenge: insights for transmission and protection(JID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Clinical and economic benefits of seasonal COVID-19 vaccination in Germany: results from the ROUTINE-COV19 Study, September 2022 to March 2024 (Eurosurveillance) Effectiveness and safety of molnupiravir among patients with mild to moderate COVID-19: a prospective, observational, cohort study (Scientific Reports) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding CoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Divergent inflammatory and neurology-related protein levels in long COVID following primary and breakthrough SARS-CoV-2 infections (Communications Medicine)  School Difficulties and Long COVID in Children and Adolescents (Academic Pediatrics) Reaching out to US house representative Letters read on TWiV 1316 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1316: Clinical update with Dr. Daniel Griffin

TWiV explains a study showing that the wildlife trade, including live-animal markets, is a major driver of animal-to-human pathogen transmission, and ecological vaccination, a strategy to prevent zoonotic spillover from bats. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Angela Mingarelli Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Bernard Roizman passes (Wikipedia) Maturation of a scientist (Ann Rev Virology) Wildlife trade drives pathogen transmission (Science) Ecological vaccination of bats (Sci Adv) Letters read  on TWiV 1315 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Angela – Real-time tracking of pathogen evolution Rich – A Precarious Perch; Suwannee’s track; Avian Research and Conservation Institute Alan – Bookshop.org Vincent – The Mysterious 30 Year Journey of Apollo 12 Listener Picks Fernando – Sean M. Carroll’s series “The Biggest Ideas in the Universe”: “Space, Time, and Motion”, and “Quanta and Fields.”  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1315: Jabs for bats

 TWiV 1314: Clinical update with Dr. Daniel Griffin April 17, 2026  In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt vaccine safety, that the head of the CDC and NIH delayed release of a report on the safety of the COVID-19m vaccine, how Nature works to spread disease without the help of the lab and the about face of the Trump administration to nominate a pro-vaccine candidate for CDC director, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how the influenza vaccine may attenuate stroke and acute cardiac disease following virus infection, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, how the COVID-19 pandemic was a ‘negative’ for one’s mortality where to go for answers about long COVID-19, potential therapies for the pediatric long COVID population and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  More Americans doubt vaccine safety than trust it, POLITICO Poll finds (Politico) Top C.D.C. Official Delays Report on Covid Shot’s Effectiveness (NY Times)  Vampire bats in Mexico may feed on CWD-positive deer, spreading disease and posing species-jump threat (CIDRAP) Emerging risks at the vampire bat–prion interface: implications for wildlife, livestock, and public health (Journal of Mammalogy)  Nine-Valent Human Papillomavirus Vaccination and Related Cancers in Males (JAMA: Oncology) Trump Administration Eyes Erica Schwartz to Lead CDC (Wall Street Journal) Trump to Nominate Doctor Who Has Publicly Supported Vaccines as C.D.C. Director (NY Times)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Measles vaccine recommendations from NYP (jpg) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots(CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) Influenza vaccination attenuates acute myocardial infarction and stroke risk following influenza infection: a register-based, self-controlled case series study, Denmark, 2014 to 2025 (Eurosurveillance)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Deep disadvantage in mortality on the frontlines of the COVID-19 pandemic (Scientific Reports) Potter’s Field (Wikipedia) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Interdisciplinary Pediatric Long-COVID Care: A Descriptive Study of Interventions and Health-Related Quality of Life (OFID) Reaching out to US house representative Letters read on TWiV 1314 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice. 

TWiV 1314: Clinical update with Dr. Daniel Griffin

TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer’s dementia, and spread of deltaviruses by a viral Trojan horse mechanism. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Dennis O’Callaghan passes (Wikipedia, LSU) Reduced dementia risk after influenza vaccine (Neurology) Deltaviruses spread via Trojan Horse (Cell) Letters read  on TWiV 1313 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Rich – The Path of Artemis II Alan – Climate change is causing cherry blossoms to miss their peak blooms in Japan Vincent – The Fabric of the Cosmos: Space, Time, and the Texture of Reality by Brian Greene Listener Picks Ann – Artemis II Launch – 7.5 Seconds in Slo-Mo Torsten – ‘This feels fragile’: how a satellite-smashing chain reaction could spiral out of control  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1313: Maybe they're all dementia vaccines

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC’s decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. coli illness in raw cheese, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, clinical practice guidelines for treating COVID-19, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, if the nasal microbiome modulates COVID-19 disease severity, reviews the use of steroid, antibiotics, anticoagulants and IVIG for treating COVID-19 including long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  State public health labs step up as CDC pauses testing for various pathogens, including rabies, mpox (CIDRAP) Infectious Diseases Laboratories : Test Directory (CDC) Kennedy rewrites the rule for membership on US vaccine advisory panel (Reuters) Advisory Committee on Immunization Practices (ACIP):  ACIP charter (CDC) Quick takes: More E coli tied to raw cheese, drug-resistant Shigella in UK, TB funds for Sudan (CIDRAP)  Voluntary Recall (FDA) E. coli Outbreak Linked to Raw Dairy (CDC: E.coli Infection (Escherichia coli)) We 100% disagree with the FDA’s false “possible link”, and extreme allegations (RawFarm USA) Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis(Neurology) US Scientists Sequence 1,000 Genomes From Measles, a Disease Long Eliminated With Vaccines (KFF HealthNews)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19 (CID) 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Baricitinib vs. Tocilizumab (CID)  ImmunobridgingAnalysis of Pemivibart for the Treatment of COVID-19 – A Therapeutic Gap for the Immune Compromised Remains (OFID) PEMGARDA® is authorized for use in certain moderately to severely immunocompromised patients to help prevent COVID-19 (Pemgarda) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Association of nasopharyngeal Dolosigranulum pigrum and Corynebacterium species with post-acute sequelae of SARS-CoV-2 in a longitudinal cohort (Microbiology Spectrum) The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge: a retrospective follow up study (Clinical and Experimental Medicine)  Intravenous immunoglobulin treatment for long COVID: a case report of clinical and immunological findings (LANCET: Infectious Diseases) Management of Orthostatic Hypotension (JAMA: Internal Medicine) Reaching out to US house representative Letters read on TWiV 1312 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1312: Clinical update with Dr. Daniel Griffin

Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories. Host: Vincent Racaniello Guests: Tony Fehr, Robin Orozco, Juergen Richt, and Rob Unckless Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV PARP14 affects replication of multiple viruses (mBio) PTPN22 allele enhances innate antiviral immunity (PNAS) Disruption of influenza in gene edited pigs (Emerg Microbes Inf) Drosophila innubila nudivirus (Virology) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1311: Jayhawks go viral

In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the “five-second” rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese before Dr. Griffin then deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, strain selection for the 2026-2027 season influenza vaccine by the FDA, if standard or high dose influenza vaccination influences dementia protection, a new variant of SARS-CoV-2, how to access and pay for Paxlovid, specific effects of Paxlovid and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  The “five-second” rule for dropped food: does it apply to dropped medical objects in the operating room? A randomized study of disinfection approaches for contaminated arthroplasty implants (Infection Control & Hospital Epidemiology) Whole Genome Sequencing (WGS) Program (FDA) Outbreak Investigation of E. coli O157:H7: Raw Cheddar Cheese (March 2026) (FDA)  Wastewater for norovirus (WasterWater Scan)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Risk of Alzheimer Dementia After High-Dose vs Standard-Dose Influenza Vaccination (Neurology) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Respiratory viral infections prime accelerated lung cancer growth (Cell) Early Detection and Surveillance of the SARS-CoV-2 Variant BA.3.2 — Worldwide, November 2024–February 2026 (CDC: MMWR) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19 (Communications Medicine) The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID (Annals of Internal Medicine) Reaching out to US house representative Letters read on TWiV 1310 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1310: Clinical update with Dr. Daniel Griffin

TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  J. Michael Bishop passes (NY Times) Vincent interviews JM Bishop (YouTube)  David Botstein passes (NY Times) Post-attachment neutralization of HPV (npj vaccines) HPV vaccine blocks infection (Cancer Discov) Respiratory viral infections prime lung cancer growth (Cell) Respiratory virus infections awaken metastatic breast cancer (TWiV 1243 ) SARS-CoV-2 mRNA vaccines sensitize tumors to immunotherapy (TWiV 1265) Letters read  on TWiV 1309 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Project Hail Mary Rich – After a decade as a Yale hospital janitor, she is now a doctor there Alan – Scientific analysis of jokes in conference talks Vincent – Yuval Noah Harari: Why advanced societies fall for mass delusion Listener Pick Greg – Changes in Terrestrial N Budgets and Riverine Nitrate-N Yields from Mississippi River Basin Watersheds 2000 to 2020  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1309: Maybe they're all cancer vaccines

In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattle against H5N1, illnesses resulting from drinking raw milk and the US norovirus outbreak, which is not cruise related, then Dr. Griffin deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, safety data of the RSV vaccine for high risk young adults, recognition of unrecognized COVID-19 deaths (but weren’t we not allow to call it a COVID-19 in 2020?), retraction of and how the ANTIBIOTIC azithromycin is NOT an antiviral drug, how to access and pay for Paxlovid, long COVID patients with neurocognitive symptoms and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Confusion abounds over future of US vaccine advisory committee (The Guardian) Key Adviser Quits Federal Vaccine Panel (NY Times) Vaccinate the vacca? …..Why We Must Vaccinate US Dairy Cattle Against HPAI H5N1(JID) Largest Animal Health Emergency in US History Continues as HPAI Hits Indiana Hard (Hoosier AG Today) Indiana: More than 350,000 birds killed in massive avian flu outbreak (CIDRAP) 5 children receive E. Coli from raw milk; TN dairy farm responds (Local 3 News) Quick takes: Measles spike in Utah, 5 kids ill from raw milk, CDC director uncertainty (CIDRAP) Increasing Predominance of Norovirus GII.17 over GII.4, United States, 2022–2025 (Emerging Infectious Diseases)  Wastewater for norovirus (WasterWater Scan)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Immunogenicity and Safety of the AS01E-adjuvanted Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine in Adults Aged 18–49 Years at Increased Risk of RSV Disease Compared with Adults Aged ≥60 Years  (CID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Respiratory viral infections prime accelerated lung cancer growth (Cell) Association between COVID-19 vaccination and sudden death in apparently healthy younger individuals: A population-based case-control study (PLoS Medicine) Applying machine learning to identify unrecognized COVID-19 deaths recorded as other causes of death in the United States (Science Advances)  RETRACTED work: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial (International Journal of Antimicrobial Agents) Antibiotic used in COVID patients tied to increased signs of antibiotic resistance (CIDRAP) Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 (Nature Microbiology)  COVID-19 mRNA Vaccination in Pregnancy and Risk of Infection in Early Childhood (Pediatrics) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Outcomes of Patients with Neurocognitive Symptoms Attending a Long COVID Clinic: A Longitudinal Cohort Study (Journal of General Internal Medicine) Outcomes of Patients withNeurocognitive Symptoms Attending a Long COVID Clinic: A Longitudinal Cohort Study (Journal of General Internal Medicine) Long COVID Treatment Guide (rthm) Reaching out to US house representative Letters read on TWiV 1308 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1308: Clinical update with Dr. Daniel Griffin

TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  Robin Weiss passes (ICR) Judge strikes down RFK Jr.’s vaccine policies (NYTimes) How Rep protein packages AAV DNA (Cell Rep) How influenza virus causes heart damage (Immunity) Influenza virus hitches a cellular ride to the heart (Cell Host Microbe) Letters read  on TWiV 1307 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – The math of March Madness brackets Kathy – SpaceX launch plume, jellyfish APOD and Cleveland Meteor, map of meteorites fall and a doorbell cam photo Rich – After barista’s tips were stolen, strangers showed up with $900 Vincent – What Causes Gravitational Time Dilation? A Physical Explanation. Listener Pick Charles – They’re Made Out Of Meat  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1307: My heart breaks for flu

In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, ‘renaming’ of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, expansion of the RSV vaccine licensure to include high risk yound adults, association between lung cancer and respiratory illnesses, how to access and pay for Paxlovid, effectiveness of vaccination or supplemental vitamin D to reduce the risk of long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Local waterfowl die-off likely caused by bird flu (The Suffolk Times) East End officials respond as dead birds pile up on Long Island shorelines (news 12: Long Island) FDA Adverse Event Monitoring System(AEMS)(FDA) FDA Launches NewAdverse Event Look-Up Tool(FDA) FDA announces AEMS, new adverse-event database to replace VAERS (CIDRAP) US cuts broad recommendation for four childhood vaccines including flu (Reuters) US CDC deploys staff to curb South Carolina’s measles outbreak (Reuters) US judge upends Kennedy’s overhaul of childhood vaccine policies (Reuters) American Academy of Pediatrics, et al v. Robert F Kennedy, Jr, et al (Civil Action No 25-11916-BEM) White House Puts RFK Jr.’s HHS on Tighter Leash After MAHA Setbacks(Wall Street Journal)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) FDA expands approval for RSV vaccine to include younger adults at high risk (FDA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Respiratory viral infections prime accelerated lung cancer growth (Cell) 2024–2025 COVID-19 mRNA Vaccine Effectiveness Against Severe Disease (JID) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of COVID-19 Vaccination and Prior Infections to Reduce Long COVID Risk During the Pre-Omicron and Omicron Periods (CID) A Randomized Trial of Vitamin D Supplementation and COVID-19 Clinical Outcomes and Long COVID: The Vitamin D for COVID-19 Trial (The Journal of Nutrition) Long COVID Treatment Guide (rthm) Reaching out to US house representative Letters read on TWiV 1306 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1306: Clinical update with Dr. Daniel Griffin

TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab accidents. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) IgNobel Prize ceremony moved to Europe (Science)  Prasad is out of the FDA (again) (npr) Sunshine virus in carpet pythons (J Virol) Selection preceding epidemics and pandemics (Cell) Letter read on TWiV 1305 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Galileo’s handwritten notes found in ancient astronomy text Rich – Dungeon Crawler Carl by Matt Dinniman Alan – High-resolution 3D imaging of the USS Monitor by NOAA’s new µSAS system Vincent – The Order of Time by Carlo Rovelli Listener Pick Douglas – Grandparents for vaccines  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1305: Lab leak idea called on the carpet

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the ‘eradicated’ poliovirus, the suggestion of RFK’s autocratic ability to change vaccine policy and the ‘resignation’ for the second time of CBER director Vinjay Prasad, and zoonotic spillover of viruses without adaptation, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, VRPBEC meeting for ‘flu’ vaccine strain selection, how to access and pay for Paxlovid, closing of long COVID treatment centers globally, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Polio: Practice enhanced precautions…..but isn’t it eradicated? (CDC: Travelers’ Health) RFK Jr has ‘unreviewable‘ authority to reshape vaccine policy, DOJ lawyer tells judge….’unreviewable’ is not even a word! (Reuters) Stark Divide: Americans More Confident in Career Scientists at U.S. Health Agencies Than Leaders (Annenberg: Public Policy Center, University of Pennsylvania) Divisive F.D.A. Vaccine Regulator Is Resigning…..for the second time in 6 months (NY Times) Characteristics and Outcomes of Patients With Hematologic Malignancies Hospitalized With Respiratory Viral Infections (OFID) Dynamics of natural selection preceding human viral epidemics and pandemics (Cell) Recent pandemic viruses, including SAR-CoV-2, spread directly to people without adaptation, researchers say (CIDRAP)  Wastewater for measles (WasterWater Scan) US CDC deploys staff to curb South Carolina’s measles outbreak (Reuters) Measles cases and outbreaks (CDC Rubeola)  Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Effectiveness of RSV Vaccines against RSV-Associated Thromboembolic Events (CDC: Emerging Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Characteristics of Young Children Hospitalized With Acute Respiratory Failure From Infection With Respiratory Syncytial Virus, SARS-CoV-2, or Both, November 2023–March 2024 (OFID) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Where are the long COVID clinics? (ScienceNews) Left without care: Many Long COVID clinics are closing down in the U.K. (The Sick Times) Where have all the Long COVID clinics gone? (The Sick Times) Reaching out to US house representative Letters read on TWiV 1304 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1304: Clinical update with Dr. Daniel Griffin

TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Shingles vaccination may slow biological aging (J Gerontol) Getting virus classification and nomenclature right (J Virol) Mucosal vaccination blocks diverse respiratory diseases (Science) Timestamps by Jolene Ramsey. Thanks!    Weekly Picks Brianne – I grew up unvaccinated. Now I’m an Immunologist Rich – Horizons from PBS News – The science behind exercise and why it’s good for our bodies; The London Busman Study (Cardiac Health) Alan – Waste Wars: The Wild Afterlife of Your Trash, by Alexander Clapp Vincent – America vs the World by Robert Kagan Listener Pick Anne – Winners of the 2026 Underwater Photographer of the Year Award  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1303: Overachieving vaccines

In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the California elephant seal population before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolinaand Utah, ICE detention centers, lack of accurate reporting may prevent the US from losing its status as a country that eliminated measles, immune amnesia from measles infection, influenza strain selection for the 2026-2027 vaccine,  recent statistics for RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, clinical trials for long COVID treatment including GLP-1 inhibitors and IVIG and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Kristen Panthagani, MD, PhD (Substack) You can know things! (Substack) Kmpanthagani: Kristen Panthagani, MD, PhD Instagram) Kristen Panthagani, MD, PhD kmpanthagani (Threads) Psychological inoculation improves resilience against misinformation on social media (Science) 5 Logical fallacies in the era of RFK Jr. (Substack) Tecovirimat for the Treatment of Mpox (NEJM) California records avian flu in northern elephant seals (CIDRAP) First Cases of Highly Pathogenic Avian Influenza in Northern Elephant Seals Confirmed in California (UC Davis)  Wastewater for measles (WasterWater Scan) The health and economic repercussions of declining MMR coverage in the United States (medRxiv) 2025 measles resurgence carries estimated $244 million price tag (CIDRAP) US builds case to retain measles elimination status as infections mount (Reuters) Expert meeting on US measles elimination status delayed to November (Reuters) ‘Nearly Every’ Child With Measles Suffers This Hidden Threat (Medscape) CDC acting director Bhattacharya urges use of measles vaccine (Reuters) Measles cases and outbreaks (CDC Rubeola)  Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services)  Utah Measles Dashboard (Utah Department of Health and Human Services) Escobar: ICE sending sick migrants to El Paso hospitals for quarantine (BorderReport) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses)  Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) RSV Detection and Antibiotic Prescribing Decisions for Pediatric Respiratory Tract Infections (JAMA Network) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2Persistence and the Gut Microbiota: New Insights into Long COVID Pathogenesis (MDPI) Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19 (Annals of Internal Medicine) Long COVID: RECOVER-TLC Clinical Trials (Foundation for the National Institute of Health) Design and rationale of RECOVER-AUTONOMIC: A randomized platform trial evaluating interventions for Long COVID postural orthostatic tachycardia syndrome (American Heart Journal)  Dr. Ruth’s Newsletter: COVID, Flu & Health News, 3/1/26 (Substack) Reaching out to US house representative Letters read on TWiV 1302 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1302: Clinical update with Dr. Daniel Griffin

TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) LCMV seroprevalence among pregnant women (Emerg Inf Dis) Giant viruses encode functional vIF4F (Cell)  Ribosomal proteins encoded in viral genomes (virology blog) Letters read on TWiV 1301 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Angela – “The Song of the Cell” by Siddhartha Mukherjee. Kathy – Fitbit for farts (WSJ and 1° article) Rich – The Password That Lets Caterpillars Hide in an Ant’s Lair Vincent – Astrophysics for People in a Hurry by Neil deGrasse Tyson Listener Pick Larry – Get an early start! (primary article)  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1301: Lost in giant virus translation

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakistan and implications for the global withdrawal of the oral poliovirus vaccine, and the outbreak of Candida, then Dr. Griffin deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  States vs RFK Jr and Bhattacharya: changes to the childhood vaccine schedule (Office of the Attorney General, California) Surgeon General Nominee Sidesteps Questions on Vaccines at Senate Hearing (NY Times)  Unqualified failure in polio vaccine policy left thousands of kids paralyzed (Science) Clinical and Epidemiological Investigation of Vaccine-Derived Poliovirus Type 2 Outbreak in Pakistan During 2019–2021 (CID) Inactivated Polio Vaccine Must Be an Essential Part of Polio Eradication (CID) Wastewater for Candida auris: Wastewater (WasterWater Scan)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)  Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium (eClinical Medicine) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1300 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1300: Clinical update with Dr. Daniel Griffin

TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email) US repeals environmental endangerment finding (Nature) Environmental groups sue EPA (Guardian) NIAID to drop pandemic preparedness and biodefense (Nature) FDA backpedals on Moderna mRNA rejection (npr) Mechanism of VITT (NEJM) Parasitc castration by a wasp virus protein (PNAS)  Polydnaviruses (PloS Path) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – The effect of seeing scientists as intellectually humble on trust in scientists and their research Rich – The Great Bridge: The Epic Story of the Building of the Brooklyn Bridge by David McCullough Alan – Recipes from the American South, by Michael Twitty Vincent – Why Returning From Mars ls Impossible – Richard Feynman’s Warning  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1299: Moth balls and blood clots

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week’s no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no experience required, and already detectable reduction in hepatitis B virus vaccination rates, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the consequences of measles infection on immune amnesia (shout out to Immune 26), long COVID treatment center, where to go for answers to your long COVID questions, long COVID effect on fertility and type 2 diabetes and contacting your federal government representative to stop the assault on science and biomedical research.     Click arrow to play Download TWiV 1298 (26 MB .mp3, 43 min) Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Whiplash! F.D.A. Reverses Decision and Agrees to Review Moderna’s Flu Vaccine (NY Times, Wall Street Journal, Access New wire)  N.I.H. Director Will Temporarily Run C.D.C. in Leadership Shake-Up (NY Times)  Reduction in infant Hepatitis B Immunizations (Oregon State Health Department) Why Adenovirus vectored vaccine failed: Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Measles Outbreak Hits Florida College (NY Times) Utah’s measles outbreak reaches 300 cases (CIDRAP) Measles Is Actively Spreading in SLCo (Salt Lake County Health Department) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Measles 2025 (NEJM) Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens (Science; Immune 26)  Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles (Science) Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands (Nature Communications) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US  respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) The risk of cardiac disease events after respiratory syncytial virus disease: a systematic literature review and meta-analysis (European Respiratory Review) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) COVID-19 Antiviral Prescription Receipt Among Outpatients Aged ≥65 Years (CDC: MMWR) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine) Long-Term Risk of Incident Type 2 Diabetes Following SARS-CoV-2 Infection: A Population-Based Study in British Columbia, Canada (Diabetes Metabolism Research and Review) Reaching out to US house representative Letters read on TWiV 1298 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1298: Clinical update with Dr. Daniel Griffin

TWiV explains the observation that filamentous virions act as non-infectious interfering particles to modulate papillomavirus infection, and transmission of monkeypox virus from fire-footed rope squirrels to sooty mangabeys. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Positions in Rosenfeld Lab (email)  FDA refuses to review Moderna flu mRNA vaccine (CIDRAP)  Oz measles vaccine call, too little too late? (dw.com) Defective human papillomavirus interfering virus particles (J Virol) Fire-footed rope squirrel potential MPXV reservoir (Nature) Squirrels could be MPXV reservoir (Nature) Letters read on TWiV 1297 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Silo TV series Kathy – Ancient RNA expression profiles from the extinct woolly mammoth and Ancient host-associated microbes obtained from mammoth remains Alan – Ubik, by Philip K. Dick Vincent – Starry Messenger by Neil deGrasse Tyson Listener Pick Beth – Iceland crime fiction authors Yrsa Sigurdardottir and Ragnar Jonasson Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1297: Spillover squirrel

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are shocked by recent events, including Dr. Oz’s appeal for measles vaccination, Vinjay Prasad’s unilateral rejection of Moderna’s mRNA influenza vaccine application, and the increasing number of New World screw worm cases, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the number of measles deaths in Mexico, long COVID treatment center, where to go for answers to your long COVID questions, choroid plexus alterations in long COVID association with neuropathologies and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  How Dr. Oz’s appeal to get measles vaccine may differ from RFK Jr.’s messaging (ABC News) FDA reverses course, refuses to review Moderna’s application for new mRNA flu vaccine (CIDRAP)  Hepatitis B Vaccination at Birth: Safety, Effectiveness, and Public Health Benefit (American Academy of Pediatrics: Pediatrics) US Olympic Committee remains ‘dialed in’ to prevent spread of stomach illness at Winter Games (CNN) Oz promotes measles vaccination (NY Times; USA Today; Fortune) Screw worm in Mexico (Gobierno de Mexico) Mexico reports more human New World screwworm infections (CIDRAP)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Measles outbreak poses risk of ‘irreversible’ brain damage, health officials warn (Fox News) In Mexico, at least 28 have died from measles outbreak that started 2025 (Reuters) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza vaccination and the risk of myocardial infarction(BMC Publich Health)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-world global database (Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Choroid plexus alterations in long COVID and their associations with Alzheimer’s disease risks (Alzheimer’s & Dementia) Reaching out to US house representative Letters read on TWiV 1296 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1296: Clinical update with Dr. Daniel Griffin

TWiV reviews a survey conducted in Cambodia's floating villages to explore measles vaccination perceptions and willingness to consider novel vaccination approaches, and how a prophage defends against an infecting phage. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Positions in Rosenfeld Lab (email) Update on US measles outbreak (npr)  Tracking Poll on Trust in the CDC and Views of Federal Childhood Vaccine Schedule Changes (KFF) Measles vaccination perceptions in Cambodia (J Virol) Prophage defends against infecting phage (Cell Host Micro) Letters read on TWiV 1295 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne - Libib book cataloging app Rich - The Mysterious Case of Rudolf Diesel: Genius, Power, and Deception on the Eve of World War I by Douglas Brunt Jolene - Ellie Jameson artwork and Redbubble Vincent - Recursion by Blake Crouch Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1295: Are YOU willing to take one for the team?

In his weekly clinical update during Ground hog week, Dr. Griffin and Vincent Racaniello are back to discuss the measles outbreak in South Carolina, American Academy of Pediatrics vaccine recommendations and shingles vaccine and the reduction of dementia, then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wastewater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, estimated effectiveness of this year’s COVID-19 vaccine, long COVID treatment center, where to go for answers to your long COVID questions, long COVID in children, the potential benefits of metformin to reduce disease severity following SARS-CoV-2 infection in obese and overweight patients and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Grading the groundhogs (National Oceanic and Atmospheric Administration) Sand Mountain Sam predicts an early spring (News19) All About the AAP Recommended Immunization Schedule (healthychildren.org)  Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics) Herpes zoster vaccination and incident dementia in Canada: an analysis of natural experiments (LANCET: Neurology) Detection of avian flu antibodies in Dutch dairy cow: ECDC risk assessment remains unchanged (European Centre for Disease Prevention and Control)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Estimated Effectiveness of 2024-2025 COVID-19 Vaccination Against Severe COVID-19 (JAMA) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR): a retrospective cohort study (LANCET: Infectious Diseases) Long COVID is here to stay—even in children (LANCET: Infectious Diseases)  Early administration of neutralising monoclonal antibodies and post-acute sequelae of COVID-19 (International Journal of Infectious Diseases) Preventing Long COVID With Metformin (CID) Metformin may reduce risk of long COVID by 64% in overweight or obese adults (CIDRAP) Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese (CID)  Preventing Long COVID With Metformin (CID) New review highlights growing evidence that diabetes drug metformin can prevent long COVID (CIDRAP) Reaching out to US house representative Letters read on TWiV 1294 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1294: Clinical update with Dr. Daniel Griffin

TWiV reviews the finding in Sweden that immunization against cervical cancer with human papillomavirus vaccine also protects the non-immunized, and methyl salicylic acid as a key volatile molecule that attracts parasitoid wasps to rice and other crops to destroy destructive leafhoppers, and is down-regulated by virus infection to enable virus spread. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Positions in Rosenfeld Lab (email) "Host adaptations to viral infections” International Meeting  William Foege dies (NY Times)  Peter Duesberg dies (NY Times) US gov't lost over 10,000 PhDs under DJT (Science) Herd effect of HPV vaccination (Lancet Pub Health) Arboviruses manipulate rice's volatile emissions (Sci Adv) Letters read on TWiV 1293 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Kathy - The Beak of the Finch, by Jonathan Weiner Rich - Washington: A Life by Ron Chernow Vincent - The Man from Beijing by Henning Mankell Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1293: The enemy of your parasite is your friend

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss with disgust the decline and fall of American public health and the rise of “only me” when highlighting completion of the US withdrawal from the WHO and possibility of making IPV and MMR optional vaccines, before Dr. Griffin then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Europe losing its measles elimination status, first measles death in Mexico, almost 1000 measles cases in South Carolina, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season’s influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  US completes withdrawal from World Health Organization (AP News) Rejecting Decades of Science, Vaccine Panel Chair Says Polio and Other Shots Should Be Optional (NY Times) A Frightening Interview (Beyond the Noise) Unexplained Pauses in Centers for Disease Control and Prevention Surveillance: Erosion of the Public Evidence Base for Health Policy (Annals of Internal Medicine)  Wastewater for measles (WasterWater Scan) UK among 6 European countries losing measles elimination status (Dougall MD: DG Alerts) European Regional Verification Commission for Measles and Rubella Elimination (RVC) (WHO: Europe) Measles Outbreak Associated with an Infectious Traveler — Colorado, May–June 2025 (CDC: MMWR) South Carolina measles cases hit 789, surpassing Texas' 2025 outbreak total (Reuters) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) States across the country report first measles cases of year(CIDRAP)  First measles death confirmed in Mexico in 2026 (Mexico News) Influenza: Waste water scan for 11  pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza Vaccine Effectiveness Among Children With and Without Underlying Conditions(Pediatrics)  OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain)  Effectiveness and Durability of the BNT162b2 KP.2 vaccine against COVID-19 Hospitalization and Emergency Department or Urgent Care Encounters in US Adults (OFID) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Association of Nirmatrelvir-ritonavir with intubation or mortality risks in severe COVID-19 patients (BMC Infectious Diseases) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1292 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1292: Clinical update with Dr. Daniel Griffin

TWiV explains emergence of a neurovirulent double recombinant from the ‘improved’ nOPV2 in Uganda, and efficiency of viral entry determined whether cells are latently or lytically infected with cytomegalovirus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Positions in Rosenfeld Lab (email) nOPV2 neurovirulent recombinant in Uganda (Nat Micro)  2023 IMB report on polio eradication Viral entry shapes HCMV latency establishment (Nat Comm) Letters read on TWiV 1291 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Dark Matter by Blake Crouch Rich – Sequoiadendron giganteum; Sequoia & Kings Canyon National Park Alan – The Murderbot Diaries book series, by Martha Wells Vincent – Surely You’re Joking, Mr. Feynman! Listener Picks Rocky – Cheetah mummies found in cave (Nature, National Geographic) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1291: A foot in the door for cytomegalovirus

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset ‘the clock’ and live forever…..you know who you are Musk, Bezos) and getting one dose of the HPV vaccine, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how losing our elimination status is the cost of doing business (going for broke is never a good business model !) where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season’s influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  New World Screwworm: Outbreak Moves into Northern Mexico……with an official tag “This is an official CDC Health Advisory” (CDC: Health Alert Network) Association between shingles vaccination andslower biological aging: Evidence from a U.S. population-based cohort study (The Journals of Gerontology series A) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM)  Herd effect of human papillomavirus vaccination on incidence of high-grade cervical lesions: (LANCET: Public Health) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Detections of Highly Pathogenic Avian Influenza in Wild Birds (USDA: Animal and Plant Health Inspection Service) Delaware, Georgia see major commercial avian flu outbreaks (CIDRAP)  Wastewater for measles (WasterWater Scan) Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR) Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC: MMWR) Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg) Tracking Measles Cases in the U.S. (Johns Hopkins) Utah measles total rises to 216; CDC deputy director says losing elimination status‘cost of doing business’ (CIDRAP) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Assessing MMR vaccination coverage gaps in US children with digital participatory surveillance (Nature Health) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Effectiveness of influenza vaccination to prevent severe disease: a systematic review and meta-analysis of test-negative design studies (CMI: Clinical Microbiology and Infection)  Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026 (Eurosurveillance) Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025 (Eurosurviellance) Current flu vaccine provides moderate protection against severe disease, interim analyses suggest (CIDRAP)  OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virusnfection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1290 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1290: Clinical update with Dr. Daniel Griffin

TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized mice by using a capsid assembly modulator. Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Positions in Rosenfeld Lab (email) Dengue virus NS1 alters mosquito midgut permeability (mBio) HBV cure with a capsid assembly modulator (Cell Host Microbe) Letters read on TWiV 1289 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Angela – How hibernating bears maintain muscle mass Alan – The flood of Chinese grad students in the 2000s was a boon to US students. Vincent – Feynman Lectures on Physics Listener Picks David – Stewart Cheifet, Host of TV’s ‘Computer Chronicles,’ Dies at 87 Charles – Last Year, and the Year to Come Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1289: Building a better hepatitis B trap

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr’s announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  7 great Danish cheeses you should know (Cheese Professor)  Norovirus in on the rise! (WasterWater Scan)  Maternal Vaccine Receipt and Infant Hospital and Emergency Visits for Influenza and Pertussis (JAMA Open) TUESDAY MEASLES UPDATE: DPH Reports 124 New Measles Cases in Upstate, New Public Exposures, and Upcoming Vaccination Opportunities (South Carolina: Department of Public Health-they have one?) Measles cases soar in South Carolina, top 400 (CIDRAP)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) North Dakota confirms pediatric flu deaths as some states note surge in flu activity (CIDRAP)  OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza) The Best Flu Drug Americans Aren’t Taking (The Atlantic) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (Lancet: Infectious Diseases) Interim Safety of RSVpreF Vaccination During Pregnancy (JAMA) Pfizer’s RSV vaccine safe to use during pregnancy, study suggests (CIDRAP) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Evaluating the Effectiveness of 2024–2025 Seasonal mRNA-1273 Vaccination Against COVID-19-Related Hospitalizations and Medically Attended COVID-19 Among Adults Aged ≥ 18 years in the United States: An Observational Matched Cohort Study (Infectious Diseases and Therapy) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Incidence and Severity of Postacute Sequelae of SARS-CoV-2 Infection in the Omicron Era: A Prospective Cohort Study (JID) Reaching out to US house representative Letters read on TWiV 1288 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1288: Clinical update with Dr. Daniel Griffin

TWiV explain the tracing of 2500 years of human betaherpesvirus 6A and 6B diversity through ancient human DNA, the effect of shingles vaccination at different stages of the dementia disease course. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Positions in Rosenfeld Lab (email) Ancient human herpesvirus 6 (Sci Adv) First through sixth diseases (Merck Manual) Effect of shingle vaccination on different stages of dementia (Cell) Letters read on TWiV 1287 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – TWiM Annotations and Resources Book for Teaching Alan – Starter Villain, by John Scalzi Rich – Redshirts: A Novel with Three Codas, by John Scalzi Vincent – Mina’s Matchbox by Yoko Ogawa Listener Picks Rona – Maggie and Millie and Molly and May by Natalie Merchant Owen – How to get the vaccines you need now Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1287: Ancient herpesviruses and modern dementia

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr’s announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Childhood Immunization Schedule by Recommendation Group (US Health and Human Service)  Recommended Child and Adolescent Immunization Schedule for Ages 18 Years or Younger (American Academy of Pediatrics)  Kennedy Scales Back the Number of Vaccines Recommended for Children (NY Times) There RFK Jr. Goes Again . . .(Wall Street Journal) Hepatitis B Vaccination is an Essential Safety Net for Newborns (Johns Hopkins Bloomberg School of Public Health)  Effectiveness and Impact of Maternal RSV Immunization and Nirsevimab on Medically Attended RSV in US Children (JAMA Pediatrics) Rotavirus (College of Physicians of Philadelphia) Hepatitis A in the Era of Vaccination (Epidemiologic Reviews)  Meningococcal Vaccination in the United States: Past, Present, And Future (Ped Drugs) Meningococcal Vaccination: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020 (CDC: MMWR) N.Y. DOH says childhood vaccine recommendations remain unchanged despite CDC’s update (Spectrum 1 News)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) South Carolina measles cases rise by 26 to 211, state health department says (Reuters) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC)  Estimated Burden of COVID-19 Illnesses, Medical Visits, Hospitalizations, and Deaths in the US From October 2022 to September 2024 (JAMA Internal Medicine) The Role of Vaccination in Maternal and Perinatal Outcomes Associated With COVID-19 in Pregnancy (JAMA) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID The COVID generation: the neurodevelopmental consequences of in-utero COVID-19 exposure (Brain, behavior and Immunity) Reaching out to US house representative Letters read on TWiV 1286 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1286: Clinical update with Dr. Daniel Griffin

TWiV reviews compelling virology themes for 2024, as heard in our 98 episodes, including 22 guests. Hosts: Vincent Racaniello and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Dismantling of science and public health in the US including TWiV 1199, TWiV 1191, TWiV 1197, TWiV 1203, TWiV 1205 , TWiV 1209, TWiV 1211, TWiV 1215, TWiV 1217,  TWiV 1219, TWiV 1221, TWiV 1223, TWiV 1225, TWiV 1227, TWiV 1231, TWiV 1233, TWiV 1241, TWiV 1243,  TWiV 1245, TWiV 1285. Herpesviruses and dementia TWiV 1187, TWiV 1207, TWiV 1249, TWiV 1263, TWIV 1233 Hepatitis B, C TWiV 1213, TWIV 1237, Chari Cohen, Stephan Urban, Thomas Tu, TWiV 1279 POTW themes/highlights Dickson Despommier passes TWIV 1195, TWiP 254, YouTube excerpt, DDD Photography, ‘Despommier’s Parasitic Diseases’ H5N1 in dairy cattle TWiV 1193, TWiV 1257, TWiV 1259 (goats), TWiV 1211 EBV and Lupus TWiV 1273 Vaccines TWiV 1209, TWiV 1265, TWiV 1267 Some classic papers TWIV 1241, TWiV 1273, TWiV 1275, TWiV 1279, TWiV 1269 Respiratory infections awaken dormant breast cancer cells TWiV 1243 Phages TWiV 1261, TWiV 1181 Letters read on TWiV 1285 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Kathy – APOD for 1/1/2026; American Kestrals Put the Cherry on Top    Primary article (open access) Vincent – Science in Your Own Back Yard by Elizabeth Cooper Listener Picks Bill – They did the Monster Slash and Elle Cordova Rona – The married scientists torn apart by a COVID bioweapon theory Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1285: Encapsidating viruses 2025

Recording after the ball drops, Dr. Griffin and Vincent Racaniello wish everyone a Happy New Year, discuss an evidence-based approach to teaching and practice medicine and reminisce on the history of vaccine development and use before their discussion about the whooping cough outbreak of 2025 in the US and falling levels of tetanus vaccination, then Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how NY state reported the greatest number of influenza confirmed infections ever in one week during the week ending Dec 20,  where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Evidence-Based Medicine: A New Approach to Teaching the Practice of Medicine (JAMA) The US has seen nearly 28,000 whooping cough cases this year. Here’s what you need to know (CNN) Vaccine History: Developments by Year (CHOP, Children’s hospital of Philadelphia: Vaccine History) Reported Incidence of notable diseases in United States: 1952 Morbidity and Mortality Weekly Report, Vol. 1, No. 54, October 26, 1953 (CDC: Stacks) As tetanus vaccination rates decline, doctors worry about rising case numbers (nbc News)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) New York State Department of Health Confirms Most Flu Cases Ever Recorded in One Week: New York State Reports 71,123 Flu Cases This Week (NY State Department of Health) Weekly surveillance report: cliff notes (CDC FluView) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Nirsevimab vs RSVpreF Vaccine for Respiratory Syncytial Virus–Related Hospitalization in Newborns (JAMA) RSV Immunization Frequently Asked Questions(American Academy of Pediatrics) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1284 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1284: Clinical update with Dr. Daniel Griffin

TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA restriction system of the host by mimicking B form DNA. Hosts: Vincent Racaniello and Jolene Ramsey Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV ASV 2026 Understanding mRNA vaccine-associated myocarditis (Sci Transl Med) T7 protein overcomes DNA restriction of host (J Mol Biol) Structure of T7 protein that mimics DNA (Mol Cell) Letters read on TWiV 1283 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Jolene – Book series Dinosaur Therapy, Dinosaur Philosophy, & Dinosaur Friendship Vincent – One Plus One Equals One: Symbiosis and the evolution of complex life by John Archibald Listener Picks Terry – Arcadia by Tom Stoppard Greg – Charctic Interactive Sea Ice Graph | National Snow and Ice Data Center Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1273: Myocarditis and mimicry

Calling out “Happy Christmas to all and to all a good-night,  Dr. Griffin and Vincent Racaniello discuss high path influenza in dairy herds in Wisconsin and Marburg virus in Ethiopia before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the slightly higher association of COVID-19 infection with death than following influenza infection, benefit of passive infant immunization with niresevimab, association of COVID-19 vaccine immunogenicity protection against severe disease in vulnerable populations, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, effect of remdesivir and nirmatrelvir/ritonavir on COVID-19 associated mortality, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  USDA Confirms Highly Pathogenic Avian Influenza in a  Dairy Herd in Wisconsin (USDA Animal and Plant Health Inspection Service) Update: Genetic Sequencing Results for Wisconsin Dairy Herd Detection of Highly Pathogenic Avian Influenza(USDA Animal and Plant Health Inspection Service) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) In call with clinicians, CDC recommends flu vaccines widely(CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) Increased 30-day Mortality Risk in Coronavirus Disease 2019 Compared to Seasonal Influenza (International Journal of Infectious Diseases) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Nirsevimab vs RSVpreF Vaccine for Respiratory Syncytial Virus–Related Hospitalization in Newborns (JAMA) RSV Immunization Frequently Asked Questions(American Academy of Pediatrics) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Association between COVID-19 vaccine immunogenicity and protection against infection and severe disease in clinically vulnerable patient populations: a systematic review and meta-analysis of observational studies (Clinical Microbiology and Infection) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) The effect of remdesivir and nirmatrelvir/ritonavir on mortality in patients hospitalized with COVID-19 during the Omicron era: an emulated target trial (Clinical Microbiology and Infection) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long-COVID research just got a big funding boost: will it find new treatments? (Nature) Reaching out to US house representative Letters read on TWiV 1282 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1282: Clinical update with Dr. Daniel Griffin

Vincent travels to Tegernsee, Germany for the Sixth Ringberg Symposium on Giant Viruses, where he talks with John Archibald, Susana Coelho, and Tom Delmont about their work on – you guessed it – giant viruses. Host: Vincent Racaniello Guests: John Archibald, Susana Coelho, and Tom Delmont Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Transposable elements shaping Ectocarpus genome (Genome Biol) Mirusviruses link herpesviruses to giant viruses (Nature) Mirusviruses predicted to reproduce in nuclei (Nat Micro) Persistent mirusvirus infection in the marine protist Aurantiochytrium (Nat Com) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1281: Sex, herpes, and plankton

In his weekly clinical update, Dr. Griffin and Vincent Racaniello protest Vinjay Prasad, head of CBER FDA Nov memo stating administration of the COVID-19 vaccine resulted in 10 children’s deaths, but are cautiously delighted by the December memo from those in CBER who dispute this data-less claim, how in 31 states pertussis vaccination rates have declined before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, of clinical outcomes of oseltamivir versus baloxavir for treating influenza infection, number deaths associated with COVID-19 hospitalizations and disease associated economic burden, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how the German government is committed to research into long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Industry laments Prasad vaccine memo (Politico) Scoop: FDA vaccine chief’s memo cited 10 pediatric Covid-19 vaccine deaths—but the agency’s own analysis found 0–7 (Inside Medicine) Whooping cough cases soar as vaccination rates drop (NBC News) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Hundreds quarantined as South Carolina measles outbreak accelerates (Washington Post) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) In call with clinicians, CDC recommends flu vaccines widely (CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) Comparison of clinical outcomes of oseltamivir versus baloxavir in outpatients with influenza: a retrospective cohort analysis (International Journal of Infectious Diseases) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of 2024–2025 COVID-19 Vaccines in Children in the United States — VISION, August 29, 2024–September 2, 2025 (CDC:MMWR)  Mortality following recovery from COVID-19 hospitalization: A long-term cohort study (International Journal of Infectious Diseases)  COVID hospitalization tied to 69% higher risk of death for up to 2 years (CIDRAP) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Comparison of work productivity losses in the United States among employees with COVID-19 at high-risk of severe disease who were untreated or treated with nirmatrelvir/ritonavir (Journal of Medical Economics) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long-COVID research just got a big funding boost: will it find new treatments?(Nature) Reaching out to US house representative Letters read on TWiV 1280 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1280: Clinical update with Dr. Daniel Griffin

TWiV reviews considerations and perspectives on phage therapy, and the Nobel Prize-winning discovery of hepatitis b virus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator ASV 2026 WHO global expert committee: no link between vaccines and autism (News-Medical) Considerations on phage therapy (Nat Comm) What is TATFAR? (CDC) History of phage therapy (one, two) JAMA Viruses that (can) make you well (TWiV 1153) The InVinceable TWiV (TWiV 145) Blumberg Nobel Lecture 1976 Particles associated with Australia antigen in patients (Nature) HBV vaccination remains vital for saving lives (Hep B Foundation) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Rich – Scientist’s cat, again, helps discover new virus Alan – Wormtalk video on politicization of screwworm spread Jolene – Arrowsmith by Sinclair Lewis Vincent – Scoop: FDA vaccine chief’s memo cited 10 pediatric Covid-19 vaccine deaths—but the agency’s own analysis found 0–7 Listener Picks David – Astronomy Picture of the Day Eric – Jesse Welles (United Health) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1279: Let hepatitis b

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the rise in norovirus infections, contamination of infant formula and botulism outbreak, confusion and response to the CDC’s ACIP decision to reverse the recommendation for a birth dose of the hepatis B virus vaccine and how states in the Northwest and Northeast are responding as well as some insurance companies, then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, South Carolina’s imposed quarantine of individuals due to their accelerated measles outbreak, neurotropism of H1N1, benefits of the RSV and COVID vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Norovirus season! (Wastewater Scan) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA: Foodborne illnesses) Botulism outbreak sickens more than 50 babies and expands to all ByHeart products (AP News) CDC advisers drop decades-old universal hepatitis B birth dose recommendation, suggest blood testing after 1 dose (CIDRAP) Health and Economic Benefits of Routine Childhood Immunizations in the Era of the Vaccines for Children Program — United States, 1994–2023 (CDC: MMWR) Universal Hepatitis B vaccination at birth: safety, effectiveness and public health impact (CIDRAP)  Recommended Child and Adolescent Immunization Schedule for Ages 18 years or younger (American Academy of Pediatrics) West Coast health experts reject RFK Jr. panel, say hepatitis B vaccines at birth should continue (The Oregonian) Statement from the Northeast Public Health Collaborative In Response to ACIP’s Hepatitis B Vote (NJ.Gov Health) Governors Denounce ACIP Recommendation on Hepatitis B Vaccination, Reaffirm Commitment to Strong, Evidence-Based Childhood Vaccination Programs (Governors Public Health Alliance)  Blue Cross and Blue Shield Companies Statement on Vaccines (Blue Cross Blue Shield)  AHIPStatement on Vaccine Coverage (AHIP) Pediatricians reject CDC advisers’ guidance, plan to continue vaccinating all newborns against hepatitis B (CIDRAP) Survey: Social media on par with CDC as trusted vaccine source (Healio)  FDA to investigate whether adult deaths linked to COVID vaccine (Washington Post) Exclusive: US FDA launches fresh safety scrutiny of approved RSV therapies for infants (Reuters) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Contemporary highly pathogenic avian influenza (H5N1) viruses retain neurotropism in human cerebral organoids (OFID) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Indiana, cases of New World screwworm in Mexico, rising US flu activity (CIDRAP) Mexico reports 92 cases of myiasis in humans caused by screwworm (Expreso.press)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Hundreds quarantined as South Carolina measles outbreak accelerates (Washington Post) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Types of Influenza Viruses (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Intensive Care Unit Stay and Mechanical Ventilation Among Adults with Respiratory Syncytial Virus-Related Hospitalization by Age and Comorbidity Status (Infectious Diseases and Therapy) Cardiovascular Events 1 Year After Respiratory Syncytial Virus Infection in Adults (JAMA: Open Network) Long-Term Illness in Adults Hospitalized for Respiratory Syncytial Virus Disease, United States, February 2022–September 2023 (CDC: Emerging Infectious Diseases) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Effectiveness of the maternal RSVpreF vaccine against severe disease in infants in Scotland, UK: a national, population-based case–control study and cohort analysis (LANCET: Infectious Diseases) Effectiveness of Nirsevimab in Preventing Respiratory Syncytial Virus-related Burden: A Test-negative Case-control Study in Infants With Bronchiolitis in Lombardy Region, Italy (The Pediatric Infectious Disease Journal)  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Maternal and Neonatal Outcomes After Respiratory Syncytial Virus Prefusion F Protein Vaccination During Pregnancy (Obstetrics & Gynecology) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) COVID-19 mRNA Vaccination and 4-Year All-Cause Mortality Among Adults Aged 18 to 59 Years in France (JAMA: Open Network)  Two-year prognosis of mRNA vaccine-related myocarditis compared with historical conventional myocarditis: a population-based cohort study (CMI: Clinical Microbiology and Infection) Where to get pemgarda (Pemgarda)  EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1278 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1278: Clinical update with Dr. Daniel Griffin

Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong. Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli Guest: Jake Scott Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Vaccine RCT spreadsheet (CIDRAP) What RFK Jr gets wrong about vaccines (Conversation) RFK Jr’s case against mRNA vaccines collapses (STAT) Too many kids’ vaccines? Think again (STAT) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Angela – Angela Palmer, science meets art (one, two) Rich – TWiV Special: A Shot of Hep B with Thomas Tu; TWiV Special: A shot of HepB with Chari Cohen Vincent – TSA is checking senior’s phones for these 5 apps Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1277: Vaccine talk with Jake Scott

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the positive side effect of the shingles vaccine on dementia outcomes and how one dose of the HPV vaccine is non-inferior to two doses, but are dismayed about the FDA’s secrecy around the inflammatory statement that the COVID-19 vaccine is linked to the death of 10 children. Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of maternal administration of the RVS vaccine or the COVID vaccine for neonates, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how celiac plexus blocks improves gastrointestinal long COVID symptoms, brain alterations and neurodegenerative processes in long COVID cognitive impairment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  The effect of shingles vaccination at different stages of the dementia disease course (Cell) FDA links 10 children’s deaths to COVID-19 vaccines. Doctors want proof (ABC News) Subject: Deaths in children due to COVID-19 vaccines and CBER’s path forward Dear Team CBER,(Washington Post) Noninferiority of One HPV Vaccine Dose to Two Doses(NEJM) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Washington state resident believed to be the first to die from a rare strain of bird flu (AP News)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Types of Influenza Viruses (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)  Maternal and Neonatal Outcomes After Respiratory Syncytial Virus Prefusion F Protein Vaccination During Pregnancy (Obstetrics & Gynecology) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of COVID-19 vaccines against post-COVID-19 condition/long COVID: systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) SARS-CoV-2Infection Versus Vaccination During Pregnancy: Implications for Placental Antibody Transfer (The Pediatric Infectious Disease Journal) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Case Report: Celiac plexus block improves gastrointestinal Long COVID symptoms (Frontiers Neuroscience) Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19 (Nature Communications) Reaching out to US house representative Letters read on TWiV 1276 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1276: Clinical update with Dr. Daniel Griffin

TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator Spliced segments of adenovirus mRNA (PNAS) An amazing sequence in adenovirus mRNA (Cell) Nobel Prize for mRNA splicing (Nobel) A predominant undecanucleotide in adenovirus late mRNAs (Cell) Splicing RNA with Phillip A. Sharp (ASM) Protein production in the gut by engineered phage (Nat Biotech) Engineered phage T4 (Curr Op Virol) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Can You Identify These Lines from Classic SciFi Novels? Kathy – Saturday Morning Physics, Photograph 51 and JCE article Rich – Wikipedia:Wiki Science Competition 2025 in the United States Jolene – Data visualization workshop Vincent – Transformer: The Deep Chemistry of Life and Death by Nick Lane Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1275: An amazing sequence and a gutsy therapy

In his weekly clinical update, Dr. Griffin and Vincent Racaniello wish everyone a Happy Thanksgiving and then decry appointment of the Louisiana State surgeon general as deputy chief of the CDC, the 3 children’s deaths during this fall’s pertussis outbreak, the Marburg virus outbreak in Ethiopia, results of the phase 1 safety trial for the novel poliovirus vaccines nOPV1 and nOPV3, and the first human death from H5N5 influenza virus infection in the US this fall, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of the cell or egg based flu or the mRNA vaccines, immunogenicity and efficacy of updated COVID-19 vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, immune and cognitive dysfunction during long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Anti-science Movement: Deputy director of CDC (X:Louisiana Office of the Surgeon General) CDC’s new deputy director is vocal critic of vaccines, advocated for ivermectin (CIDRAP) Whooping cough cases on the rise in Texas (FOX4: KDFW) Third infant in Kentucky dies of whooping cough as national cases stay high for second year in a row (CIDRAP) More than 25,000 whooping cough cases reported this year as Kentucky records 3rd infant death (ABC News) Vaccination Coverage and Exemptions among Kindergartners (CDC: SchoolVaxView) Effects of human papillomavirus (HPV) vaccination programmes on community rates of HPV‐related disease and harms from vaccination (Cochrane Library) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Safety and immunogenicity of novel live attenuated type 1 and type 3 oral poliomyelitis vaccines in healthy adults in the USA: a first-in-human, observer-masked, multicentre, phase 1 randomised controlled trial (LANCET: Infectious Diseases) Washington state resident believed to be the first to die from a rare strain of bird flu (AP News)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Superior Effectiveness and Estimated Public Health Impact of Cell- Versus Egg-Based Influenza Vaccines in Children and Adults During the US 2023–2024 Season (Infectious Diseases and Therapy) Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine(NEJM) ACIP Recommendations Summary (CDC: Influenza) Types of Influenza Viruses (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Estimating Risk of Guillain-Barré Syndrome in US Medicare-Enrolled Older Adults Following Medically Attended Respiratory Syncytial Virus Disease (CID)  FDA Requires Guillain-Barré Syndrome (GBS) Warning in the Prescribing Information for RSV Vaccines Abrysvo and Arexvy: FDA Safety Communication (FDA) Brag Sets Off a Chain Reaction — Dr. Oz Takes the Bait, But Fumbles the Math, and Starts Unraveling Mid-Interview (Atlanta BlackStar) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study (LANCET: Infectious Diseases) Immunogenicity of JN.1- and KP.2-Encoding mRNA COVID-19 Vaccines Against JN.1 Subvariants in Adult Participants (OFID) SARS-CoV-2 vaccination and myositis in Norway and Sweden (Rheumatology) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Digitally Assessed Long COVID Symptomatology Is Associated With Lymphocyte Mitochondrial Dysfunction and Altered Immune Potential (OFID) Evaluation of Interventions for Cognitive Symptoms in Long COVID (JAMA Neurology) Reaching out to US house representative Letters read on TWiV 1274 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1274: Clinical update with Dr. Daniel Griffin

TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator  CDC revives debunked ‘link’ between childhood vaccines and autism (npr) A structure for deoxyribose nucleic acid (Nature pdf) Three Papers, Three Lessons (Am J Resp Crit Care Med) Discovery of Double Helix (Crick Papers) Jim Watson was blinded by DNA (NY Times) What Rosalind Franklin contributed (Nature) EBV reprograms autoreactive B-cells in lupus (Sci Transl Med) EBV and the making of lupus (Sci Transl Med) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Virus snowflakes Kathy – When “Physic(k)s Lost Its ‘k’ and other Language Quarks Vincent – The Peripheral by William Gibson Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1273: EBV and lupus have not escaped our notice

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed by the changes on CDC vaccine website positively stating the link between autism and vaccination, the finding of wild type poliovirus 1 in Germany, Marburg virus in Ethiopia, decimation of the elephant breeding colony by H5N1 and the first human case of H5N5 influenza virus infection before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, antibody escape by seasonal flu viruses, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if resistance exercise aids in recovery from long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Autism and Vaccines (CDC: Vaccine Safety) A new road to eradication- WPV 1 in Germany from Afghanistan (Reuters) Ethiopia confirms first outbreak of Marburg virus disease (WHO: Ethiopia) Highly Pathogenic Avian Influenza Viruses (HPAIV) Associated with Major Southern Elephant Seal Decline at South Georgia (Communications Biology) Avian flu has decimated world’s largest breeding colony of southern elephant seals (CIDRAP) Washington resident is infected with a different type of bird flu (AP News) Pelagic Seabirds (OceanAminals) That sounds far away: Multiple transatlantic incursions of highly pathogenic avian influenza clade 2.3.4.4b A(H5N5) virus into North America and spillover to mammals (Cell Reports) Regional voices, different choices: Parents’ and caregivers’ HPV vaccine attitudes in the northeast and Southeast United States (Vaccine)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Emergence of seasonal influenza A(H3N2) variants with immune escape potential warrants enhanced molecular and epidemiological surveillance for the 2025–2026 season (University of Toronto Press) Types of Influenza Viruses (CDC: Influenza (flu)) With an absent CDC and mismatched ‘subclade K’ flu strain, experts face upcoming season with uncertainty (CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection)  Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-word global database (Journal of Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Estimating Risk of Guillain-Barré Syndrome in US Medicare-Enrolled Older Adults Following Medically Attended Respiratory Syncytial Virus Disease (CID)  FDA Requires Guillain-Barré Syndrome (GBS) Warning in the Prescribing Information for RSV Vaccines Abrysvo and Arexvy: FDA Safety Communication (FDA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) COVID-19 vaccination is associated with reduced complications in pediatric patients with atopic dermatitis (Annals of Allergy, Asthma and Immunology) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) Risk mitigation of shared room ventilation and filtration on SARS-CoV-2 transmission: a multicenter test-negative study (Infection Control and Hospital Epidemiology)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID  Resistance Exercise Therapy After COVID-19 Infection(JAMA Open Network) Reaching out to US house representative Letters read on TWiV 1272 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1272: Clinical update with Dr. Daniel Griffin

Vincent visits Virginia Tech for the CeZAP Symposium and speaks with XJ Meng and Kylene Kehn-Hall about their research on hepatitis E virus and Rift Valley fever virus.    Host: Vincent Racaniello Guests: XJ Meng and Kylene Kehn-Hall Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator  Hepatitis E virus (Curr Op Micro) Rift Valley fever virus NSs and autophagy (PLoS Path) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1271: Hokies go viral II

In his weekly clinical update, Dr. Griffin and Vincent Racaniello record from the ASTMH meeting in Toronto and discuss continuing avian flu outbreaks, the continued global measles outbreak, the effectiveness of high and low doses of the influenza vaccine before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, children hospitalizations following COVID-19 and influenza vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  Five new avian flu outbreaks confirmed in ducks, turkeys in 3 US states (CIDRAP) Confirmation of highly pathogenic Avian Influenza in Commercial and Backyard flocks (USDA: Animal and Plant Health Inspection Service)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD) (LANCET) Relative effectiveness of the high-dose versus standard-dose influenza vaccines for the prevention of laboratory-confirmed influenza among Italian older adults during three recent seasons (International Journal of Infectious Diseases) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection)  Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-word global database (Journal of Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) COVID-19 and influenza deaths in Australian children 2018-2023: a national case analysis (Journal of Pediatric Infectious Diseases Society) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1270 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1270: Clinical update with Dr. Daniel Griffin

TWiV reviews the passing of James D. Watson, the research that showed human papillomaviruses to be present in genital and laryngeal papillomas and in some cervical cancers, and influenza virus infection, shedding and symptoms in a human challenge study. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator  James D. Watson dies (NY Times)  Russian translation of TWiV 1024 (Medium) Canada’s new budget aims to lure US researchers (Science) Bird flu surging and spreading while US agencies are asleep (npr) US slashed WHO budget, now flu surveillance is suffering globally (npr) HPV sequences in papillomas and cervical cancers (PNAS) zur Hausen Nobel Prize 2008 (Nobel) Vincent interviews zur Hausen (YouTube) Influenza virus infection, shedding, and disease in humans (J Virol) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Pandemic board game Rich – Whiskey Fungus Fed by Jack Daniel’s Encrusts a Tennessee Town Alan – Rats can snatch bats out of the air and eat them Vincent – 7 basic science discoveries that changed the world Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1269: The smell of influenza in the morning

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode   Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267) Cancers Caused by HPV (CDC: Human papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP))  HPV Vaccination Recommendation (CDC: Vaccines & Immunizations)  Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network) Review: Human H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP) Avian flu strikes turkey farms in Dakotas, large egg facility in California (CIDRAP) Another Doctor at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC)  Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Real-World Effectiveness of Nirmatrelvir-Ritonavir in Preventing Coronavirus Disease 2019–Associated Hospitalization (CID)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2 spike-specific IgG4 class switching associates with clinical recovery in Long COVID (Journal of Infection) Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy) Preventive effect of vaccination on long COVID in adolescents with SARS-CoV-2 infection (Vaccine) Reaching out to US house representative Letters read on TWiV 1268 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1268: Clinical update with Dr. Daniel Griffin

TWiV discusses the impact of vaccinating with Gardasil-9 adult women who are human papillomavirus positive or with confirmed squamous intraepithelial lesions, and human monoclonal antibodies that target the monkeypox virus A35 protein which protect against lethal disease. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator Long tailed macaques are now officially endangered (Science) Iceland now has mosquitoes (npr) Impact of Gardasil-9 on adult women who are HPV+ or SIL+ (Viruses) Human mAbs that protect against mpox disease (Cell) Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Brianne – Civet coffee: The real chemistry behind this bizarre luxury drink Kathy – Astronomy photographer of the year awards Rich – Katherine Swan Ginsburg Humanism in Medicine Program Alan – Parasitic worms can use static electricity to latch onto flies midair Vincent – How to get the best night’s sleep: what the science says Listener Pick Bradon – Elevated Access Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1267: A cancer vaccine and an mpox treatment

In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if revaccination with the mRNA RSV vaccine is effective, how effective today’s COVID-19 vaccine is for protection against severe disease following infection with current viral variants, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV: TWiV 1265) Viral Infections and Risk of Cardiovascular Disease (Journal of the American Heart Association) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 (NEJM)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola))  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Measles vaccine recommendations from NYP (jpg) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: Cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan)  Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Safety, Tolerability, and Immunogenicity of Revaccination With mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged ≥50 Years (CID) Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England (LANCET: Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans (NEJM) Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants (JAMA: Internal Medicine) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1266 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1266: Clinical update with Dr. Daniel Griffin

TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Immune 100 live at the Incubator SARS-CoV-2 mRNA vaccines sensitize tumors to checkpoint immunotherapy (Nature) People with some cancers live longer after mRNA vaccines (Nature) Immune checkpoint inhibitors (NCI) Broad immunity from influenza H5 vaccine (Nature) Derek Smith on antigenic cartography (TWiV 99 at 2:53) Letters read on TWiV 1265 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Kathy – Permethrin-treated baby wraps for malaria prevention and Phil Sharp and the Biotech Revolution Rich – Lydia Fairchild; Tetragametic Chimerism (NEJM) Alan – Warning Signs Vincent – radio.garden thanks to Kim! Listener Pick Jamie – SkyCards by Flightradar24 Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1265: mRNA vaccines make cancer treatment great again

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are distressed by the continuing government shutdown, first locally acquired chikungunya virus infection, President Trump’s suggestion for removing aluminum from vaccines, H5N1 isolation from backyard birds and turkey farms, and the suggestion of establishing an alternative to the CDC’s MMWR and asymptomatic measles infections before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the quarantining in the US due to measles, access to anti-influenza antiviral, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if colchicine is effective for long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV!  Links for this episode  New York health officials confirm state’s first locally acquired case of chikungunya virus (AP News) Trump Rattles Vaccine Experts Over Aluminum (NY Times) Aluminum-Adsorbed Vaccines and Chronic Diseases in Childhood (Annals of Internal Medicine) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Jeffrey Lee McLean (California.No) California mpox cases raise concerns. But health officials say the risk remains low (AP News) ‘Alternative’ to CDC’s Flagship Journal in the Works (MEDPAGE TODAY) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) Frustration grows amid measles outbreak quarantines across several states (NBC News) More Than 100 Cases of Measles Reported in Utah and Arizona (NY Times)  Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health)  Measles (CDC Measles (Rubeola)) Measles vaccine recommendations from NYP (jpg)  Presumptive evidence of measles immunity (CDC)  Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza)  American Academy of Pediatrics Flu and Children (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) Roche to sell flu pill for $50 to cash-paying US patients (Reuters) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))  Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)  Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library) Estimated Vaccine Effectiveness for Respiratory Syncytial Virus–Related Acute Respiratory Illness in Older Adults (CID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda)  EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions)  CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS)  Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC)  Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of Colchicine for the Treatment of Long COVID(JAMA Internal Medicine) Reaching out to US house representative Letters read on TWiV 1264 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks!  Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV 1264: Clinical update with Dr. Daniel Griffin

TWiV reviews continuing US measles outbreak, host and genetic variations that regulate antibody responses to hepatitis C virus, and varicella-zoster reactivation and the risk of dementia. Hosts: Vincent Racaniello, Alan Dove, Brianne Barker, and Angela Mingarelli Subscribe (free):  Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode  Support science education at MicrobeTV Mass firings at CDC (Time) Measles cases continue to climb in US (NPR)  Immune 100 at The Incubator (Eventbrite) Viral and host variations modulate antibody responses against HCV (Cell Rep) VZV reactivation and risk of dementia (Nature Med) Taking a shot at dementia (TWiV 1207) Demented and crass (TWiV 1249) Letters read on TWiV 1263 Timestamps by Jolene Ramsey. Thanks!  Weekly Picks Angela – ‘Am I redundant?’: how AI changed my career in bioinformatics Brianne – OpenSpace and their YouTube Channel Alan – Coral City Camera – live view of a reef in Biscayne Bay, FL (and NPR story on it). Vincent – Neck pain relief exercises with Dr. Adam Fields Listener Pick Greg – AI: What could go wrong? and An AI System With Detailed Diagnostic Reasoning Makes Its Case Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.